Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed

L B A van de Putte; C Atkins; M Malaise; J Sany; A S Russell; P L C M van Riel; L Settas; J W Bijlsma; S Todesco; M Dougados; P Nash; P Emery; N Walter; M Kaul; S Fischkoff; H Kupper

doi:10.1136/ard.2003.013052

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Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed

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	Abstract	Full	Pdf
Mar 2004	0	1	0
Apr 2004	205	375	336
May 2004	202	354	308
Jun 2004	111	250	134
Jul 2004	70	172	96
Aug 2004	63	181	65
Sep 2004	50	101	81
Oct 2004	42	74	61
Nov 2004	44	125	87
Dec 2004	25	69	62
Jan 2005	54	93	80
Feb 2005	30	120	64
Mar 2005	30	83	96
Apr 2005	13	74	44
May 2005	22	99	129
Jun 2005	25	99	114
Jul 2005	18	79	91
Aug 2005	21	89	90
Sep 2005	9	61	64
Oct 2005	29	89	89
Nov 2005	36	83	90
Dec 2005	16	59	56
Jan 2006	8	88	68
Feb 2006	23	99	73
Mar 2006	20	96	83
Apr 2006	18	96	95
May 2006	25	60	60
Jun 2006	27	39	39
Jul 2006	17	61	61
Aug 2006	38	79	74
Sep 2006	25	58	54
Oct 2006	32	70	63
Nov 2006	26	77	59
Dec 2006	30	49	43
Jan 2007	39	66	65
Feb 2007	30	77	72
Mar 2007	57	71	93
Apr 2007	67	25	43
May 2007	43	29	28
Jun 2007	40	24	23
Jul 2007	33	19	37
Aug 2007	41	26	29
Sep 2007	41	27	49
Oct 2007	37	17	33
Nov 2007	43	28	31
Dec 2007	16	8	18
Jan 2008	35	22	34
Feb 2008	49	28	44
Mar 2008	54	23	26
Apr 2008	55	27	46
May 2008	60	26	49
Jun 2008	56	29	39
Jul 2008	55	16	44
Aug 2008	49	28	41
Sep 2008	65	32	50
Oct 2008	44	29	32
Nov 2008	59	34	48
Dec 2008	43	23	41
Jan 2009	50	26	28
Feb 2009	76	31	44
Mar 2009	96	33	49
Apr 2009	61	24	62
May 2009	51	20	34
Jun 2009	75	23	29
Jul 2009	60	22	33
Aug 2009	64	18	43
Sep 2009	49	17	42
Oct 2009	65	16	37
Nov 2009	72	19	36
Dec 2009	59	10	35
Jan 2010	45	17	25
Feb 2010	48	21	29
Mar 2010	75	26	49
Apr 2010	45	29	30
May 2010	37	23	28
Jun 2010	41	18	25
Jul 2010	35	18	44
Aug 2010	34	17	30
Sep 2010	31	15	5
Oct 2010	48	17	17
Nov 2010	45	17	28
Dec 2010	33	7	10
Jan 2011	33	19	19
Feb 2011	55	25	28
Mar 2011	50	35	35
Apr 2011	31	31	23
May 2011	42	17	25
Jun 2011	47	12	24
Jul 2011	32	12	17
Aug 2011	50	25	29
Sep 2011	48	17	29
Oct 2011	57	17	29
Nov 2011	43	48	27
Dec 2011	43	32	33
Jan 2012	55	39	31
Feb 2012	44	33	52
Mar 2012	64	34	43
Apr 2012	54	44	45
May 2012	56	42	41
Jun 2012	59	39	38
Jul 2012	71	37	41
Aug 2012	57	42	34
Sep 2012	83	46	41
Oct 2012	73	63	51
Nov 2012	74	43	33
Dec 2012	81	55	55
Jan 2013	81	62	41
Feb 2013	98	87	64
Mar 2013	84	83	44
Apr 2013	101	91	59
May 2013	79	53	39
Jun 2013	63	52	36
Jul 2013	58	44	42
Aug 2013	57	71	39
Sep 2013	74	75	45
Oct 2013	86	88	64
Nov 2013	87	90	65
Dec 2013	60	51	30
Jan 2014	67	56	38
Feb 2014	65	82	62
Mar 2014	102	118	46
Apr 2014	79	125	53
May 2014	68	126	46
Jun 2014	73	78	37
Jul 2014	73	73	32
Aug 2014	64	107	35
Sep 2014	69	130	39
Oct 2014	58	154	37
Nov 2014	32	142	35
Dec 2014	35	81	29
Jan 2015	41	83	20
Feb 2015	53	101	47
Mar 2015	111	101	51
Apr 2015	61	87	45
May 2015	49	61	37
Jun 2015	59	77	25
Jul 2015	62	49	31
Aug 2015	40	59	20
Sep 2015	60	77	32
Oct 2015	51	60	20
Nov 2015	51	49	33
Dec 2015	60	59	26
Jan 2016	92	62	43
Feb 2016	36	48	35
Mar 2016	19	77	42
Apr 2016	34	89	36
May 2016	36	73	32
Jun 2016	41	65	18
Jul 2016	63	37	27
Aug 2016	68	57	24
Sep 2016	111	61	33
Oct 2016	108	64	30
Nov 2016	142	72	32
Dec 2016	93	70	35
Jan 2017	133	109	35
Feb 2017	45	91	58
Mar 2017	36	130	39
Apr 2017	38	159	54
May 2017	22	100	38
Jun 2017	66	91	50
Jul 2017	129	99	35
Aug 2017	166	123	30
Sep 2017	159	118	21
Oct 2017	210	120	34
Nov 2017	160	96	28
Dec 2017	143	79	22
Jan 2018	134	90	30
Feb 2018	137	102	24
Mar 2018	130	71	42
Apr 2018	152	80	48
May 2018	107	80	32
Jun 2018	130	88	32
Jul 2018	150	108	36
Aug 2018	116	88	24
Sep 2018	151	107	28
Oct 2018	152	116	33
Nov 2018	138	94	28
Dec 2018	112	88	22
Jan 2019	201	143	61
Feb 2019	109	73	28
Mar 2019	230	143	82
Apr 2019	150	118	42
May 2019	95	85	31
Jun 2019	136	104	33
Jul 2019	107	89	36
Aug 2019	117	91	39
Sep 2019	112	68	34
Oct 2019	137	100	43
Nov 2019	173	149	38
Dec 2019	123	112	31
Jan 2020	184	144	31
Feb 2020	119	97	48
Mar 2020	341	266	69
Apr 2020	241	193	55
May 2020	130	116	39
Jun 2020	145	123	62
Jul 2020	131	112	39
Aug 2020	107	83	57
Sep 2020	157	122	93
Oct 2020	133	116	45
Nov 2020	167	138	52
Dec 2020	148	122	29
Jan 2021	157	126	58
Feb 2021	248	213	62
Mar 2021	348	296	93
Apr 2021	214	188	46
May 2021	242	225	60
Jun 2021	142	142	39
Jul 2021	144	144	51
Aug 2021	113	113	28
Sep 2021	134	134	34
Oct 2021	239	211	70
Nov 2021	200	173	81
Dec 2021	223	196	43
Jan 2022	180	142	40
Feb 2022	199	167	45
Mar 2022	432	398	97
Apr 2022	297	255	68
May 2022	207	180	48
Jun 2022	215	214	41
Jul 2022	244	222	36
Aug 2022	264	237	53
Sep 2022	261	244	59
Oct 2022	246	229	44
Nov 2022	337	307	63
Dec 2022	235	194	39
Jan 2023	290	256	45
Feb 2023	324	316	54
Mar 2023	551	520	98
Apr 2023	265	254	50
May 2023	318	283	90
Jun 2023	262	240	66
Jul 2023	276	264	67
Aug 2023	288	266	76
Total	23070	22067	11254

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