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Letter
Autoantibodies against glucose-6-phosphate isomerase are not a diagnostic marker for juvenile idiopathic arthritis
  1. A Schmitt1,
  2. D Schubert1,
  3. C Sengler2,
  4. T Kamradt1
  1. 1Deutsches Rheumaforschungszentrum Berlin, 10117 Berlin, Germany
  2. 2Universitätsklinikum Charité, Department of Paediatrics, 10098 Berlin, Germany
  1. Correspondence to:
    Dr T Kamradt
    Deutsches Rheumaforschungszentrum, Schumannstr 20/21, 10117 Berlin, Germany; Kamradtdrfz.de

https://doi.org/10.1136/ard.2003.014225

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    Rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) are chronic inflammatory diseases that primarily affect the joints. The triggers that activate autoreactive T and B lymphocytes in arthritic patients are still unknown.1 It has been widely assumed, however, that the autoantigens recognised by arthritogenic lymphocytes are joint-specific. This assumption has been challenged by findings from a murine model of …

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