The second edition of Osteoarthritis is a very well documented and illustrated book. The different chapters cover perfectly the most important questions relating to osteoarthritis—epidemiology, socioeconomics, genetics, pathogenesis, clinical features, and management both in daily practice and clinical trials. In particular, there are well documented sections on specific investigations such as biological markers, magnetic resonance imaging, and ultrasonography. Moreover, two sections evaluate more fully the potential modifiers of cartilage breakdown. This book will be useful for all who are involved in osteoarthritis research and/or in charge of the management of osteoarthritic patients.