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Primary Raynaud’s phenomenon in monozygotic twins
  1. T Oskay1,
  2. Ü Ölmez2
  1. 1Department of Dermatology Bayındır Medical Centre Ankara, Turkey
  2. 2Department of Clinical Immunology and Rheumatology, Ankara University Faculty of Medicine Ankara, Turkey
  1. Correspondence to:
    Dr T Oskay
    Mesa Park Sitesi Sedir Apt, Daire: 44 06400 Oran, Ankara, Turkey;

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We report two cases of primary Raynaud’s phenomenon in 16 year old monozygotic female twins.


The twins were admitted to the dermatology department with a one year history of the sudden onset of episodic purple lesions on both hands. Presentation of the lesions in the twins was synchronous. After careful questioning, we determined that it was usually induced by emotion or cold temperature. On dermatological examination, the order of purple discolouration, erythema, and pallor was observed symmetrically in both hands. There was no history of smoking, the use of drugs, occupational hazard, or trauma. They also had sensations of coolness and paraesthesia. Photographs of the hands were obtained during an attack and used to confirm the history. We also performed a provocative test—namely, immersion …

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