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Clinical predictors of fetal and maternal outcome in Chinese patients with systemic lupus erythematosus
  1. M Y Mok1,
  2. P Y Leung1,
  3. T H Lao2,
  4. Y Lo1,
  5. T M Chan1,
  6. W S Wong1,
  7. C S Lau1
  1. 1Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong
  2. 2Department of Obstetrics and Gynaecology, Queen Mary Hospital, Pokfulam Road, Hong Kong
  1. Correspondence to:
    Dr M Y Mok
    4/F, Professorial Block Department of Medicine, Queen Mary Hospital Pokfulam Road, Hong Kong; mymoknetvigator.com

https://doi.org/10.1136/ard.2004.022442

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    Maternal and fetal outcome of pregnancy in patients with systemic lupus erythematosus (SLE) depends very much on the composition of the patient cohort being analysed.

    METHODS AND RESULTS

    We performed a retrospective study to identify the clinical predictive factors for unfavourable pregnancy outcome in our Chinese patients with SLE from a homogeneous cohort being followed up at the university rheumatology clinic during the period 1982–96. Ninety one pregnancies from 66 patients were identified. Antiphospholipid antibodies (aPL), including lupus anticoagulant (LAC) and/or IgG anticardiolipin antibodies, were present in 18/66 (27%) patients. In 33/80 (41%) pregnancies resulting in live births, patients had a past history of lupus nephritis. Only one patient had impaired renal function, two had significant proteinuria ⩾1 g/day, and four had stable hypertension while receiving antihypertensive drugs …

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