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Anti-Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy
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  • Published on:
    Author's reply
    • Ilse E Hoffman, MD
    • Other Contributors:
      • Martine De Vos, Filip De Keyser

    Dear Editor

    We thank dr Barta for his comments on our manuscript ‘anti- Saccharomyces cerevisiae IgA antibodies are raised in ankylosing spondylitis and undifferentiated spondyloarthropathy’.[1]

    We are fully aware of the importance of gut inflammation in spondyloarthropathies (SpA).[2] In our view, the finding of ASCA in SpA provides further evidence for the concept that inflammatory bowel disease and SpA...

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    Conflict of Interest:
    None declared.
  • Published on:
    ASCA and spondyloarthropathy: with or without gut inflammation?

    Dear Editor

    Anti-Saccharomyces cerevisiae antibodies (ASCA) are known as specific markers in Crohn's disease albeit the clinical relevance of these antibodies to some oligomannose epitope of the Saccharomyces cerevisiae is not clear. Neither the origin and nor the clinicopathological role are clarified.

    Hoffman et al, investigated whether ASCAs are present in spondyloarthropathies (SpA) in comparison w...

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    Conflict of Interest:
    None declared.