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Review
Antiphospholipid antibodies and infections
  1. R A Asherson1,
  2. R Cervera2
  1. 1Rheumatic Diseases Unit, Department of Medicine, University of Cape Town School of Medicine and Groote Schuur Hospital, Cape Town, South Africa
  2. 2Department of Autoimmune Diseases, Institut Clínic d’Infeccions i Immunologia, Hospital Clínic, Barcelona, Catalonia, Spain
  1. Correspondence to:
    Dr R Cervera, Servei de Malalties Autoimmunes, Hospital Clínic, Villarroel, 170. 08036 Barcelona, Catalonia, Spain;
    rcervera{at}clinic.ub.es

Abstract

Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as “autoimmune” and “infectious” types. This distinction, however, has subsequently been found not to be absolute.

  • antiphospholipid antibodies
  • infections
  • aCL, anticardiolipin antibodies
  • AIDS, acquired immunodeficiency syndrome
  • aPL, antiphospholipid antibodies
  • APS, antiphospholipid syndrome
  • CMV, cytomegalovirus
  • EBV, Epstein-Barr virus
  • HCV, hepatitis C virus
  • HIV, human immunodeficiency virus
  • HTLV, human T lymphotrophic virus
  • LA, lupus anticoagulant
  • PHT, pulmonary hypertension
  • SLE, systemic lupus erythematosus
  • TTP, thrombotic thrombocytopenic purpura
  • VDRL, Venereal Disease Research Laboratory test

https://doi.org/10.1136/ard.62.5.388

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