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The diagnosis of central nervous system (CNS) manifestations in systemic lupus erythematous (SLE) is often difficult. These manifestations may be explained by a number of aetiologies. Here, we discuss the possible role of Fahr’s disease in an elderly patient with lupus CNS manifestations. Fahr’s disease is characterised by idiopathic, sporadic, extensive, and symmetric striatopallidodentate calcifications, with calcium deposits in the cerebral basal ganglia, dentate nuclei, and both the cerebral and cerebellar cortex.1 It is often asymptomatic and discovered during brain imaging.2 However, it has been associated with neurological manifestations including hemichorea, Parkinson’s disease, epilepsy, and dementia.3
A 76 year old woman was admitted to the hospital in February 1998 for a non-destructive inflammatory polyarthritis, which had started in 1997. At that time, she developed a right pleural effusion with a non-regenerative anaemia and neutropenia. In addition, she had high levels of …