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Cerebral calcifications in an elderly lupus patient
  1. V Filloux,
  2. H Marotte,
  3. P Miossec
  1. Departments of Immunology and Rheumatology, Hôpital Edouard Hérriot, Lyon, France
  1. Correspondence to:
    Professor P Miossec, Clinical Immunology Unit, Departments of Immunology and Rheumatology, Hôpital Edouard Hérriot, 69437 Lyon Cedex 03, France;
    miossec{at}univ-lyon1.fr

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The diagnosis of central nervous system (CNS) manifestations in systemic lupus erythematous (SLE) is often difficult. These manifestations may be explained by a number of aetiologies. Here, we discuss the possible role of Fahr’s disease in an elderly patient with lupus CNS manifestations. Fahr’s disease is characterised by idiopathic, sporadic, extensive, and symmetric striatopallidodentate calcifications, with calcium deposits in the cerebral basal ganglia, dentate nuclei, and both the cerebral and cerebellar cortex.1 It is often asymptomatic and discovered during brain imaging.2 However, it has been associated with neurological manifestations including hemichorea, Parkinson’s disease, epilepsy, and dementia.3

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