Insoluble and soluble immune complexes activate neutrophils by distinct activation mechanisms: changes in functional responses induced by priming with cytokines

G Fossati; R C Bucknall; S W Edwards

doi:10.1136/ard.61.1.13

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Extended report

Insoluble and soluble immune complexes activate neutrophils by distinct activation mechanisms: changes in functional responses induced by priming with cytokines

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	Abstract	Full	Pdf
Jan 2002	42	102	38
Feb 2002	5	55	21
Mar 2002	4	21	9
Apr 2002	7	36	16
May 2002	5	19	1
Jun 2002	7	22	7
Jul 2002	5	21	6
Aug 2002	4	17	10
Sep 2002	7	8	3
Oct 2002	4	11	3
Nov 2002	1	25	7
Dec 2002	1	10	7
Jan 2003	2	25	15
Feb 2003	2	21	4
Mar 2003	2	21	12
Apr 2003	2	11	4
May 2003	2	7	5
Jun 2003	0	4	8
Jul 2003	8	14	8
Aug 2003	10	10	7
Sep 2003	8	16	2
Oct 2003	12	68	6
Nov 2003	14	17	5
Dec 2003	12	16	3
Jan 2004	18	45	2
Feb 2004	11	16	5
Mar 2004	11	9	3
Apr 2004	19	19	5
May 2004	33	45	5
Jun 2004	40	42	7
Jul 2004	39	41	10
Aug 2004	25	45	9
Sep 2004	25	71	8
Oct 2004	10	75	8
Nov 2004	15	39	13
Dec 2004	10	40	10
Jan 2005	11	35	24
Feb 2005	6	53	12
Mar 2005	9	34	12
Apr 2005	3	24	4
May 2005	7	22	8
Jun 2005	11	22	13
Jul 2005	2	11	5
Aug 2005	2	20	13
Sep 2005	2	23	8
Oct 2005	5	27	9
Nov 2005	4	27	8
Dec 2005	1	28	8
Jan 2006	3	24	6
Feb 2006	4	20	2
Mar 2006	3	26	7
Apr 2006	0	10	7
May 2006	4	10	1
Jun 2006	1	7	9
Jul 2006	2	12	7
Aug 2006	1	11	7
Sep 2006	3	17	3
Oct 2006	5	21	7
Nov 2006	7	32	13
Dec 2006	5	22	8
Jan 2007	5	28	14
Feb 2007	3	25	9
Mar 2007	4	34	11
Apr 2007	10	8	6
May 2007	8	7	7
Jun 2007	10	6	8
Jul 2007	8	15	6
Aug 2007	4	14	9
Sep 2007	4	4	2
Oct 2007	3	3	0
Nov 2007	14	3	2
Dec 2007	9	0	0
Jan 2008	4	6	5
Feb 2008	7	6	4
Mar 2008	23	3	2
Apr 2008	7	3	2
May 2008	12	1	3
Jun 2008	7	3	2
Jul 2008	15	2	2
Aug 2008	22	3	3
Sep 2008	28	3	0
Oct 2008	33	3	2
Nov 2008	19	1	1
Dec 2008	7	2	3
Jan 2009	5	5	3
Feb 2009	13	4	1
Mar 2009	29	5	4
Apr 2009	14	1	3
May 2009	7	4	1
Jun 2009	15	4	2
Jul 2009	7	2	1
Aug 2009	3	4	3
Sep 2009	15	0	2
Oct 2009	33	5	2
Nov 2009	45	2	1
Dec 2009	11	1	11
Jan 2010	8	12	9
Feb 2010	3	4	3
Mar 2010	6	1	2
Apr 2010	5	10	2
May 2010	4	2	0
Jun 2010	13	12	7
Jul 2010	8	3	3
Aug 2010	5	7	4
Sep 2010	8	8	4
Oct 2010	11	6	3
Nov 2010	9	19	8
Dec 2010	10	5	5
Jan 2011	11	6	3
Feb 2011	8	8	2
Mar 2011	11	12	2
Apr 2011	11	4	1
May 2011	9	6	7
Jun 2011	8	7	6
Jul 2011	16	1	2
Aug 2011	12	4	2
Sep 2011	11	10	5
Oct 2011	18	3	3
Nov 2011	11	13	0
Dec 2011	16	23	7
Jan 2012	8	9	5
Feb 2012	14	31	6
Mar 2012	16	13	12
Apr 2012	4	21	6
May 2012	8	20	5
Jun 2012	9	15	7
Jul 2012	9	28	9
Aug 2012	9	13	8
Sep 2012	9	26	10
Oct 2012	11	21	12
Nov 2012	11	25	13
Dec 2012	14	17	3
Jan 2013	10	18	7
Feb 2013	11	33	12
Mar 2013	16	25	8
Apr 2013	16	25	16
May 2013	15	37	7
Jun 2013	5	10	3
Jul 2013	8	13	7
Aug 2013	9	7	5
Sep 2013	7	8	2
Oct 2013	6	18	6
Nov 2013	5	13	4
Dec 2013	7	12	3
Jan 2014	7	6	2
Feb 2014	1	11	7
Mar 2014	19	21	3
Apr 2014	7	14	3
May 2014	14	24	5
Jun 2014	3	11	2
Jul 2014	19	21	10
Aug 2014	3	7	86
Sep 2014	6	11	5
Oct 2014	13	11	6
Nov 2014	6	11	4
Dec 2014	7	19	6
Jan 2015	3	12	8
Feb 2015	5	14	6
Mar 2015	4	12	4
Apr 2015	6	15	2
May 2015	4	10	4
Jun 2015	6	12	3
Jul 2015	12	10	4
Aug 2015	5	9	3
Sep 2015	22	20	5
Oct 2015	1	6	1
Nov 2015	2	9	1
Dec 2015	13	12	1
Jan 2016	7	15	4
Feb 2016	10	14	5
Mar 2016	12	15	12
Apr 2016	11	8	5
May 2016	15	11	4
Jun 2016	14	11	6
Jul 2016	6	13	3
Aug 2016	9	3	4
Sep 2016	15	11	5
Oct 2016	6	14	14
Nov 2016	11	12	6
Dec 2016	12	31	3
Jan 2017	11	305	2
Feb 2017	1	183	2
Mar 2017	3	14	4
Apr 2017	3	21	2
May 2017	4	23	2
Jun 2017	4	20	5
Jul 2017	16	14	1
Aug 2017	26	27	3
Sep 2017	21	19	0
Oct 2017	21	21	2
Nov 2017	23	24	3
Dec 2017	15	15	1
Jan 2018	24	20	5
Feb 2018	34	32	7
Mar 2018	18	14	2
Apr 2018	24	20	3
May 2018	18	14	2
Jun 2018	56	55	11
Jul 2018	44	44	10
Aug 2018	84	76	6
Sep 2018	41	41	4
Oct 2018	96	94	8
Nov 2018	111	111	6
Dec 2018	86	84	2
Jan 2019	70	68	4
Feb 2019	64	63	8
Mar 2019	60	61	9
Apr 2019	53	51	14
May 2019	44	41	6
Jun 2019	46	43	12
Jul 2019	41	41	6
Aug 2019	29	29	5
Sep 2019	43	44	9
Oct 2019	58	56	9
Nov 2019	55	55	4
Dec 2019	53	51	8
Jan 2020	60	59	9
Feb 2020	42	39	6
Mar 2020	45	43	11
Apr 2020	43	43	8
May 2020	51	51	11
Jun 2020	36	28	11
Jul 2020	44	44	12
Aug 2020	30	30	3
Sep 2020	58	54	3
Oct 2020	59	59	5
Nov 2020	55	54	14
Dec 2020	51	47	0
Jan 2021	58	58	10
Feb 2021	33	32	8
Mar 2021	40	36	6
Apr 2021	34	34	5
May 2021	33	31	40
Jun 2021	46	46	18
Jul 2021	22	23	7
Aug 2021	51	51	14
Sep 2021	50	50	20
Oct 2021	70	67	17
Nov 2021	59	60	33
Dec 2021	51	49	14
Jan 2022	43	39	4
Feb 2022	54	50	9
Mar 2022	96	87	28
Apr 2022	70	68	7
May 2022	78	84	26
Jun 2022	54	58	13
Jul 2022	67	62	12
Aug 2022	75	69	8
Sep 2022	70	72	15
Oct 2022	104	104	17
Nov 2022	99	100	22
Dec 2022	61	57	4
Jan 2023	69	71	11
Feb 2023	95	93	9
Mar 2023	94	94	14
Apr 2023	31	31	12
May 2023	59	59	12
Jun 2023	67	68	6
Jul 2023	47	49	15
Aug 2023	58	57	18
Total	5683	7286	1882

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