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THU0217 Joint hipermobility sindrome: a prospective study of articular and non-rheumatic manifestation in a venezuelan population
  1. F Riano,
  2. O Sanchez,
  3. N Pena,
  4. Z Tinedo
  1. Rheumatology, Hospital Central Maracay, Maracay, Venezuela


Objectives Although Joint Hypermobility Sindrome (JHS) is a common condition, there are clearly a number of articular and non-articular manifestations. Because of this, one study of subjects with JHS was performed in our country.

Methods A prospective, descriptive and analytical of 41 patients attending our Unit from February up to September 1999, and who fulfilled the Beighton Scale for JHS (Beighton P, Grahame R, Bird H (1999) Assessment of hipermobility. In Beighton P (ed) Hypermobility of Joints. Spring, London, pp:9–22) was made. The mean age was 32 years, there were 35 females (85.4%) and 6 males (14.6%). All over the group were evaluated through Beighton Scale (BS), being 4 points the lowest and 9 points the highest. All subjects were examined for echocardiogram and a gynaecological exam was performed in all sexually active women.

Results 11 patients (26.8%) had 9 points in the BS and 1 patient (2.4%), being the mean of the group of 6 points. The dorsiflexion of fifth finger was found in all subjects. When comparing passive apposition of the thumb of the flexor aspect of the forearm, with the highest point, there was a good correlation (p = 0.003). Patients under 30 years had higher points in the BS (p = 0.005). Arthralgia was present in 29 subjects (70.78%), mainly in women (p = 0.001). Flat feet was found in 23 patients (56.09%) and Marfanoid habitus in 23 patients. Mitral valve prolapse (MVP) was found in 24 patients (58.53%), the great majority under 30 years and with higher points in the BS. Uterine prolapse was diagnosed in 12 women of the 24 examined (50.0%), most of them over 30 years, no significance correlation was showed between uterine prolapse and points in the BS.

Conclusion In our study arthralgias particularly of the knees was found, and among extrarticular MVP was the commonest one. We also found a higher incidence of uterine prolapse than expected for women in this age.

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