Article Text

Download PDFPDF
Remission of Behçet's syndrome with tumour necrosis factor α blocking therapy
  1. P H Goossens,
  2. R J Verburg,
  3. F C Breedveld
  1. Department of Rheumatology, Leiden University Medical Centre, The Netherlands
  1. Professor F C Breedveld, Department of Rheumatology, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlandsf.c.breedveld{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

A 40 year old man presented in 1986 with painful noduli and skin ulcers on his foot. Based on a deep skin biopsy, showing obliteration of the vascular lumen with necrosis and infiltration of lymphocytes in the vascular wall, a diagnosis of polyarteritis nodosa was made. Treatment with prednisone (40 mg daily) was started, but because of persistent disease activity azathioprine (150 mg/day) and, subsequently, cyclophosphamide (100 mg/day) was added. Despite this treatment, the symptoms recurred periodically. In subsequent years he became steroid …

View Full Text