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Cutaneous leucocytoclastic vasculitis caused by cyclosporin A (Sandimmun)
  1. M N GUPTA,
  2. R D STURROCK
  1. G GUPTA
  1. Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow
  2. Department of Dermatology, Glasgow Royal Infirmary, Glasgow
  1. Dr G Gupta, Department of Dermatology, Monklands Hospital, Monklands Avenue, Airdrie, Lanarkshire ML6 0JS

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Cutaneous leucocytoclastic vasculitis to cyclosporin A (Sandimmun) has not been previously described. We report the case of a 37 year old man who presented with a 10 day history of a purpuric eruption affecting both legs. He had been diagnosed as having psoriasis and psoriatic arthropathy 12 years previously, on the basis of joint symptoms, sacroileitis, erosive arthropathy, increased acute phase reactants and positive HLA B27 status. His initial treatments had included oral gold (Auranofin) 3 mg three times per day and salazopyrine 3 g/day. Both were discontinued because of poor control of his …

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