Article Text

Download PDFPDF
Does social disadvantage contribute to the excess mortality in rheumatoid arthritis patients?
  1. N Maiden,
  2. H A Capell,
  3. R Madhok,
  4. R Hampson,
  5. E A Thomson
  1. Centre for Rheumatic Diseases, Royal Infirmary , Castle Street, Glasgow G4 0SF
  1. Dr H A Capell.


BACKGROUND Socioeconomic deprivation is associated with increased mortality from cardiovascular causes and malignancy. The influence of disadvantage in patients with rheumatoid arthritis (RA), who are known to have premature mortality, has not been ascertained.

AIM To assess the relation between the level of patient deprivation and mortality in RA patients.

METHODS 200 RA patients, enrolled in a study comparing sulfasalazine and penicillamine in 1984–85, have been followed up prospectively for 12 years. Subjects were categorised into Carstairs groups with deprivation scores ranging from 1 (most affluent) to 7 (most deprived). Information about deaths was obtained from the Registrar General in Scotland, death certificates and GP/hospital records.

RESULTS There were more RA patients in the deprived areas then expected compared with the West of Scotland and England and Wales. Some 47.5% of the RA patients had died by 12 years—the majority of cardiorespiratory causes or malignancy. There were no differences in the median age or disease duration in the various Carstairs groups at study entry, but the percentage of deaths was higher in the more deprived groups after 12 years (36% dead in most affluent area compared with 61% in the most deprived, that is, in groups 6 and 7).

CONCLUSION In patients with RA increasing deprivation was associated with premature mortality. If confirmed elsewhere these findings have implications for rheumatological management strategies, for researchers involved in collaborative studies of patients from different socioeconomic backgrounds and for resource allocation.

  • rheumatoid arthritis
  • mortality
  • socioeconomic status

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.