Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components

Maxime Dougados; Bernard Combe; Alain Cantagrel; Philippe Goupille; Patrick Olive; Manfred Schattenkirchner; S Meusser; L Paimela; Rolf Rau; Henning Zeidler; Marjatta Leirisalo-Repo; Kristiina Peldan

doi:10.1136/ard.58.4.220

Article metrics

Extended reports

Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components

Online download statistics by month:

Online download statistics by month: April 1999 to November 2024

	Abstract	Full	Pdf
Apr 1999	162	411	106
May 1999	24	51	16
Jun 1999	13	33	11
Jul 1999	9	6	3
Aug 1999	3	7	2
Sep 1999	3	7	1
Oct 1999	5	9	3
Nov 1999	3	5	8
Dec 1999	2	3	0
Jan 2000	4	16	7
Feb 2000	2	7	5
Mar 2000	4	7	31
Apr 2000	4	9	2
May 2000	2	13	4
Jun 2000	2	2	0
Jul 2000	4	4	4
Aug 2000	3	6	0
Sep 2000	2	2	4
Oct 2000	2	5	3
Nov 2000	2	7	8
Dec 2000	2	7	10
Jan 2001	2	3	5
Feb 2001	1	8	4
Mar 2001	3	13	14
Apr 2001	4	11	3
May 2001	3	40	1
Jun 2001	4	5	2
Jul 2001	2	5	1
Aug 2001	0	10	8
Sep 2001	3	5	4
Oct 2001	2	9	3
Nov 2001	3	8	4
Dec 2001	1	4	1
Jan 2002	3	10	3
Feb 2002	1	8	10
Mar 2002	4	10	7
Apr 2002	4	16	1
May 2002	0	7	2
Jun 2002	4	5	0
Jul 2002	3	7	2
Aug 2002	4	7	7
Sep 2002	3	20	10
Oct 2002	7	14	7
Nov 2002	4	8	9
Dec 2002	4	11	9
Jan 2003	4	7	4
Feb 2003	6	8	7
Mar 2003	5	11	7
Apr 2003	3	15	7
May 2003	5	15	11
Jun 2003	4	10	6
Jul 2003	18	126	11
Aug 2003	22	16	8
Sep 2003	24	21	6
Oct 2003	18	64	8
Nov 2003	21	33	17
Dec 2003	25	19	11
Jan 2004	32	58	11
Feb 2004	19	12	6
Mar 2004	23	29	13
Apr 2004	25	31	9
May 2004	48	48	14
Jun 2004	53	67	16
Jul 2004	47	68	17
Aug 2004	39	53	16
Sep 2004	34	80	12
Oct 2004	15	76	27
Nov 2004	15	49	29
Dec 2004	15	42	15
Jan 2005	10	63	11
Feb 2005	11	38	9
Mar 2005	23	38	19
Apr 2005	11	36	16
May 2005	18	37	35
Jun 2005	23	10	12
Jul 2005	11	34	36
Aug 2005	15	39	25
Sep 2005	9	47	16
Oct 2005	13	47	27
Nov 2005	14	31	17
Dec 2005	12	36	17
Jan 2006	10	39	19
Feb 2006	13	42	18
Mar 2006	5	39	10
Apr 2006	5	35	18
May 2006	19	40	23
Jun 2006	23	17	14
Jul 2006	19	16	12
Aug 2006	23	26	13
Sep 2006	21	23	27
Oct 2006	23	29	25
Nov 2006	24	26	24
Dec 2006	20	20	19
Jan 2007	17	36	29
Feb 2007	17	41	16
Mar 2007	20	48	26
Apr 2007	20	13	10
May 2007	20	10	9
Jun 2007	26	8	8
Jul 2007	17	10	10
Aug 2007	19	11	10
Sep 2007	15	9	6
Oct 2007	26	18	17
Nov 2007	22	9	15
Dec 2007	18	11	10
Jan 2008	31	14	13
Feb 2008	34	8	9
Mar 2008	28	17	9
Apr 2008	24	6	11
May 2008	24	3	6
Jun 2008	24	4	16
Jul 2008	20	6	15
Aug 2008	14	4	6
Sep 2008	21	8	15
Oct 2008	33	8	17
Nov 2008	36	1	9
Dec 2008	22	3	1
Jan 2009	22	6	10
Feb 2009	12	11	2
Mar 2009	31	11	11
Apr 2009	12	11	12
May 2009	22	5	6
Jun 2009	22	7	11
Jul 2009	17	3	4
Aug 2009	12	4	7
Sep 2009	29	3	7
Oct 2009	25	17	17
Nov 2009	25	3	10
Dec 2009	40	4	10
Jan 2010	26	4	7
Feb 2010	21	1	11
Mar 2010	26	4	6
Apr 2010	10	7	4
May 2010	11	8	6
Jun 2010	21	8	8
Jul 2010	22	7	12
Aug 2010	25	5	11
Sep 2010	23	4	4
Oct 2010	16	9	6
Nov 2010	16	5	6
Dec 2010	20	11	9
Jan 2011	23	5	8
Feb 2011	12	5	6
Mar 2011	24	7	11
Apr 2011	22	5	5
May 2011	16	3	5
Jun 2011	21	3	4
Jul 2011	24	1	4
Aug 2011	20	1	10
Sep 2011	21	1	1
Oct 2011	28	3	3
Nov 2011	33	8	7
Dec 2011	15	10	19
Jan 2012	16	10	16
Feb 2012	14	8	4
Mar 2012	36	15	7
Apr 2012	29	25	13
May 2012	19	13	11
Jun 2012	22	14	14
Jul 2012	33	11	16
Aug 2012	15	22	11
Sep 2012	32	12	19
Oct 2012	46	15	15
Nov 2012	29	17	10
Dec 2012	38	24	13
Jan 2013	55	26	18
Feb 2013	34	13	10
Mar 2013	30	18	11
Apr 2013	29	21	18
May 2013	38	18	13
Jun 2013	20	12	8
Jul 2013	39	13	10
Aug 2013	22	11	12
Sep 2013	20	11	7
Oct 2013	48	26	10
Nov 2013	26	22	6
Dec 2013	23	18	16
Jan 2014	28	23	20
Feb 2014	26	22	13
Mar 2014	35	41	17
Apr 2014	30	65	9
May 2014	34	116	16
Jun 2014	12	107	12
Jul 2014	37	53	15
Aug 2014	13	33	13
Sep 2014	28	33	12
Oct 2014	56	29	23
Nov 2014	21	12	13
Dec 2014	32	31	8
Jan 2015	16	12	5
Feb 2015	10	26	24
Mar 2015	17	36	8
Apr 2015	21	59	7
May 2015	22	29	17
Jun 2015	16	43	11
Jul 2015	25	45	7
Aug 2015	18	56	14
Sep 2015	43	28	12
Oct 2015	22	32	9
Nov 2015	10	19	9
Dec 2015	39	28	17
Jan 2016	80	21	16
Feb 2016	20	26	11
Mar 2016	23	7	9
Apr 2016	32	16	9
May 2016	21	17	13
Jun 2016	17	11	9
Jul 2016	29	22	12
Aug 2016	19	9	7
Sep 2016	21	18	9
Oct 2016	32	31	20
Nov 2016	24	17	14
Dec 2016	14	16	4
Jan 2017	24	11	9
Feb 2017	13	18	13
Mar 2017	9	28	9
Apr 2017	4	29	27
May 2017	11	21	4
Jun 2017	13	34	2
Jul 2017	31	27	5
Aug 2017	35	22	7
Sep 2017	36	26	6
Oct 2017	51	31	6
Nov 2017	36	22	11
Dec 2017	41	27	9
Jan 2018	76	58	4
Feb 2018	146	132	10
Mar 2018	84	65	11
Apr 2018	87	77	7
May 2018	65	53	3
Jun 2018	56	44	11
Jul 2018	45	35	7
Aug 2018	45	39	11
Sep 2018	56	44	12
Oct 2018	72	56	18
Nov 2018	66	56	16
Dec 2018	88	74	10
Jan 2019	61	44	11
Feb 2019	43	36	5
Mar 2019	58	43	18
Apr 2019	16	14	11
May 2019	31	21	15
Jun 2019	25	17	11
Jul 2019	34	14	11
Aug 2019	18	16	14
Sep 2019	28	15	9
Oct 2019	48	26	18
Nov 2019	18	12	7
Dec 2019	37	26	15
Jan 2020	38	32	11
Feb 2020	43	34	16
Mar 2020	40	17	16
Apr 2020	18	14	9
May 2020	33	21	20
Jun 2020	17	15	10
Jul 2020	41	24	10
Aug 2020	34	23	10
Sep 2020	50	32	23
Oct 2020	40	33	11
Nov 2020	37	23	9
Dec 2020	35	24	7
Jan 2021	26	19	11
Feb 2021	22	18	14
Mar 2021	32	28	10
Apr 2021	22	20	8
May 2021	35	31	8
Jun 2021	38	37	18
Jul 2021	18	18	8
Aug 2021	16	15	9
Sep 2021	34	28	5
Oct 2021	37	31	26
Nov 2021	51	37	31
Dec 2021	44	35	10
Jan 2022	40	42	20
Feb 2022	45	51	19
Mar 2022	32	23	11
Apr 2022	42	34	9
May 2022	41	35	16
Jun 2022	56	42	14
Jul 2022	39	35	19
Aug 2022	45	41	12
Sep 2022	56	46	14
Oct 2022	165	162	16
Nov 2022	58	49	9
Dec 2022	34	32	14
Jan 2023	47	41	6
Feb 2023	66	61	6
Mar 2023	18	19	13
Apr 2023	47	32	29
May 2023	35	29	11
Jun 2023	23	21	13
Jul 2023	27	23	5
Aug 2023	18	14	6
Sep 2023	27	19	4
Oct 2023	45	40	14
Nov 2023	77	56	9
Dec 2023	121	55	3
Jan 2024	78	19	1
Feb 2024	98	15	0
Mar 2024	173	6	4
Apr 2024	146	32	4
May 2024	94	14	0
Jun 2024	46	12	2
Jul 2024	99	10	4
Aug 2024	133	12	2
Sep 2024	106	16	4
Oct 2024	92	8	1
Nov 2024	320	21	3
Total	9187	7816	3400

Log in using your username and password

Main menu

Log in using your username and password

You are here

Online download statistics by month:

Online download statistics by month: April 1999 to November 2024

Read the full text or download the PDF:

Log in using your username and password