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Research Article
Induction of remission in a patient with Takayasu's arteritis by low dose pulses of methotrexate.
  1. D Mevorach,
  2. G Leibowitz,
  3. M Brezis,
  4. E Raz
  1. Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.

    Abstract

    A 42 year old woman with Takayasu's arteritis responded to treatment with prednisone (60 mg daily) but developed severe side effects. Cyclophosphamide treatment did not produce a clinical improvement or steroid sparing effect. A treatment trial with a weekly pulse of low dose methotrexate improved her symptoms and the patency of her occluded left subclavian artery.

    https://doi.org/10.1136/ard.51.7.904

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