Article Text

Download PDFPDF

What is the contribution of occupational environmental factors to the occurrence of scleroderma in men?
  1. A J Silman,
  2. S Jones
  1. Arthritis and Rheumatism Council, Epidemiology Research Unit, University of Manchester, United Kingdom.


    An occupational analysis of 56 men with scleroderma in the United Kingdom showed no evidence that silica exposure was implicated in the onset of the disease, in contrast with older published reports suggesting that such exposure explained an important proportion of the occurrence of the disease in men. Of the major occupational exposures suggested from case reports, only organic solvents were reported to any extent in this series. No significant increase in exposure to organic solvents was noted, however, in a case control analysis.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.