Article Text

Download PDFPDF

Systemic lupus erythematosus in the elderly: clinical and immunological characteristics.
  1. J Font,
  2. L Pallarés,
  3. R Cervera,
  4. A López-Soto,
  5. M Navarro,
  6. X Bosch,
  7. M Ingelmo
  1. Department of Internal Medicine, Hospital Clínic i Provincial, Barcelona, Spain.


    Systemic lupus erythematosus (SLE) predominantly affects young women in their 20s. In 40 out of 250 (16%) patients with SLE seen in our hospital disease onset occurred after the age of 50. The interval between the time of onset and diagnosis was five years in this older group compared with three years in the younger group. Arthritis, as a first symptom, was less common in the older onset group. During the follow up a lower incidence of arthritis, malar rash, photosensitivity, and nephropathy was found in the older onset group. In contrast, this group showed an increased incidence of myositis. High titres of anti-dsDNA tended to occur less often and the incidence of anti-Ro antibodies was lower in the older onset group. These features seem to distinguish patients with older onset SLE as a particular subset.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.