Article Text

Download PDFPDF

Degradation of human cartilage by synovial fluid but not cytokines in vitro.
  1. A P Hollander,
  2. R M Atkins,
  3. D M Eastwood,
  4. P A Dieppe,
  5. C J Elson
  1. Department of Pathology, University of Bristol, UK.


    Synovial fluids from patients with rheumatoid arthritis and from patients with osteoarthritis degraded the matrix of living, but not killed, normal human cartilage as judged by loss of glycosaminoglycans. Normal human serum did not degrade living cartilage and neither, unexpectedly, did recombinant human cytokines.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Linked Articles