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Arthritis associated with adjuvant mycobacterial treatment for carcinoma of the bladder.
  1. R A Hughes,
  2. S A Allard,
  3. R N Maini
  1. Department of Immunology of Rheumatic Disease, Charing Cross Hospital, London.


    A patient who developed an inflammatory polyarthritis following intravesical administration of bacillus Calmette-Guérin (BCG) used in the treatment of bladder cancer is described. An inflammatory synovitis comprising predominantly T lymphocytes was demonstrated on synovial biopsy. The synovitis resolved spontaneously within 14 days in this 'human model' of adjuvant arthritis.

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