Article Text


Acute confusional state and hyponatraemia due to inappropriate antidiuretic hormone secretion in polyarteritis nodosa.
  1. J S Gaston,
  2. D G Scott,
  3. P A Bacon
  1. Department of Rheumatology, Medical School, University of Birmingham, UK.


    An acute confusional state, which developed in a patient with polyarteritis nodosa (PAN), proved to be secondary to inappropriate secretion of antidiuretic hormone and consequent hyponatraemia. This is a very unusual complication of PAN and may well reflect a direct stimulation of the supraoptic nuclei owing to cerebral vasculitis.

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