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Renal findings in rheumatoid arthritis: clinical aspects of 132 necropsies.
  1. M Boers,
  2. A M Croonen,
  3. B A Dijkmans,
  4. F C Breedveld,
  5. F Eulderink,
  6. A Cats,
  7. J J Weening
  1. Department of Rheumatology, Leiden University, The Netherlands.


    Renal abnormalities in 132 necropsied patients with rheumatoid arthritis were studied. Clinical findings before death included extra-articular manifestations of the disease (86% of patients), systemic vasculitis (6%), and uraemia (23%). Necropsy findings included nephrosclerosis (90%), systemic vasculitis (14%) with kidney involvement in 8%, amyloidosis (11%), membranous glomerulopathy (8%), and focal glomerular disease (8%). Association with clinical data suggests that both rheumatoid and non-rheumatoid disease may play a part in the cause of these abnormalities.

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