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A new promising treatment in systemic sclerosis: 5-fluorouracil.
  1. J A Casas,
  2. C P Subauste,
  3. G S Alarcón
  1. Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.


    Twelve patients with systemic sclerosis according to American Rheumatism Association criteria were treated with intravenous 5-fluorouracil. Significant subjective and objective improvement occurred initially in the skin and subsequently in the involved viscera and vasculature. These preliminary results suggest that 5-fluorouracil may be an effective treatment for systemic sclerosis.

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