In a prospective study serum C-reactive protein (CRP) concentrations were measured during 28 febrile episodes in 27 Oriental patients with systemic lupus erythematosus (SLE). Although active SLE was associated with only a modest rise in serum CRP level, intercurrent infection provoked substantially higher levels. Serum CRP thus provides a sensitive objective test for this complication in SLE patients of all ethnic groups.
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