You are here

Article Text

Article menu

Download PDFPDF

Research Article
Leukotriene B4, a mediator of inflammation present in synovial fluid in rheumatoid arthritis.
  1. E M Davidson,
  2. S A Rae,
  3. M J Smith

    Abstract

    Leukotriene B4 (LTB4), generated from arachidonic acid following lipoxygenase activity by a variety of inflammatory leucocytes, has been shown to be present in synovial fluid from patients with active rheumatoid arthritis. It does not persist as such, being converted to less active metabolites. The role of LTB4 as one of the natural mediators of inflammation is discussed.

    https://doi.org/10.1136/ard.42.6.677

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.