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Late-onset peripheral joint disease in ankylosing spondylitis
  1. Marc D. Cohen,
  2. William W. Ginsburg
  1. Division of Rheumatology and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA


    We reviewed the records of 150 patients with definite ankylosing spondylitis who had significant peripheral arthritis and were seronegative and found 7 patients who had the onset of peripheral arthritis after their spinal disease became inactive. This late-onset peripheral arthritis may lead to significant joint deformity, and aggressive therapy may be warranted.

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