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Prospective analysis of antiribonucleoprotein antibodies in systemic lupus erythematosus.
  1. B Bresnihan,
  2. R Grigor,
  3. G R Hughes


    A prospective analysis of 50 successive patients with systemic lupus erythematosus, seen over a 4-year period, has been completed. 336 sera were examined for the presence of antibody to ribonucleoprotein using a counterimmunoelectrophoresis assay. Antibody was present in the sera of 16% of patients and was detectable in about the same titre throughout the course of the disease. The presence of the antibody did not appear to identify a subgroup of lupus patients with individual clinical characteristics.

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