Systemic lupus erythematosus

Evolution of anti-DNA autoantibodies by somatic hypermutation: evidence for postmutational B cell tolerance
Kristin Schroeder, Ute Wellmann, Thomas H Winkler, Martin Herrmann

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A32; DOI: 10.1136/annrheumdis-2011-201234.1
Uptake of SLE autoantibodies by podocytes
Anja Hillmann, Hedda Wardemann, Thomas Pap, Annett Jacobi

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A32-A33; DOI: 10.1136/annrheumdis-2011-201234.2
B lymphocytes can regulate the maturation and function of human dendritic cells but are partially inefficient in systemic lupus erythematosus
Ahsen Morva, Sébastien Lemoine, Achouak Achour, Alain Saraux, Jacques-Olivier Pers, Pierre Youinou, Christophe Jamin

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A34; DOI: 10.1136/annrheumdis-2011-201234.6
Decreased immunoregulatory activity of B cells derived from patients with systemic lupus erythematosus
Theresa Tretter, Nele Gao, Julia Dresel, Rimma Gellert, Hanns-Martin Lorenz

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A35; DOI: 10.1136/annrheumdis-2011-201234.8
Autoantibodies to the functionally active RING-domain of Ro52/SSA associate with clinical activity in a subset of patients with lupus
Marika Kvarnström, Vijole Dzikaite, Lars Ottosson, Iva Gunnarsson, Elisabet Svenungsson, Marie Wahren-Herlenius

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A40; DOI: 10.1136/annrheumdis-2011-201234.19
Helios+ FoxP3+ naturally occurring regulatory T cells are peripherally expanded in active systemic lupus erythematosus
Tobias Alexander, Lars Templin, Siegfried Kohler, Christian Groß, Arne Sattler, Andreas Meisel, Gerd-Rüdiger Burmester, Andreas Radbruch, Andreas Thiel, Falk Hiepe

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A41-A42; DOI: 10.1136/annrheumdis-2011-201234.23
Investigating the cellular composition of lymph nodes in preclinical and early inflammatory arthritis: a feasibility study
L G M van Baarsen, M J H de Hair, T H Ramwadhdoebe, M van de Sande, I J A J Zijlstra, M Maas, D M Gerlag, P P Tak

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A20; DOI: 10.1136/annrheumdis-2011-201231.4
Outer membrane vesicles containing autocitrullinated peptidylarginine deiminase from Porphyromonas gingivalis part of an infection model in RA?
M Sohn, B Marklein, G R Burmester, K Skriner

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A27-A28; DOI: 10.1136/annrheumdis-2011-201232.5
IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE – a possible new treatment?
Christian Lood, Maria Allhorn, Rolf Lood, Birgitta Gullstrand, Anders I Olin, Lars Rönnblom, Gunnar Sturfelt, Lennart Truedsson, Mattias Collin, Anders A Bengtsson

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A1; DOI: 10.1136/annrheumdis-2011-201230.2
Systems biology of SLE: biochemical characterisation of subgroups within sle for improved diagnosis and treatment
Helena Idborg, Ganna Oliynyk, Stefan Rännar, Jenny Forshed, Rui Mamede Branca, Magdalena Donten, Johanna Gustafsson, Anna Vikerfors, Iva Gunnarsson, Johan Trygg, Janne Lehtiö, Torbjörn Lundstedt, Elisabet Svenungsson, Per-Johan Jakobsson

Annals of the Rheumatic Diseases Feb 2012, 71 (Suppl 1) A12; DOI: 10.1136/annrheumdis-2011-201230.27

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