Online First

An exciting innovation allowing the advanced publication of selected articles within days of acceptance.

Online First articles are available as unedited manuscripts* in downloadable PDF form
They are peer reviewed, accepted for publication and indexed by PubMed but not yet included in a journal issue.

* edited, typeset versions may be added as they become available

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To see an article (subscription required for full text), click its [Accepted Manuscript] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

6 August 2008

Esperanza Naredo, Carlos Acebes, Ingrid Möller, Fernando Canillas, Juan José de Agustín, Eugenio de Miguel, Emilio Filippucci, Annamaria Iagnocco, Carmen Moragues, Roser Tuneu, Jacqueline Uson, Jesús Garrido, Emilio Delgado-Baeza, and Iván Sáenz-Navarro: Ultrasound validity in the measurement of knee cartilage thickness
Ann Rheum Dis Published Online First: 6 August 2008. doi:10.1136/ard.2008.090738 [Abstract] [Accepted Manuscript]

P J Mease, P Ory, J T Sharp, C T Ritchlin, F van den Bosch, F Wellborne, C Birbara, G TD Thomson, R J Perdok, J Medich, R L Wong, and D D Gladman: Adalimumab for long-term treatment of psoriatic arthritis: two-year data from the Adalimumab Effectiveness in Psoriatic Arthritis Trial (ADEPT)
Ann Rheum Dis Published Online First: 6 August 2008. doi:10.1136/ard.2008.092767 [Abstract] [Accepted Manuscript]

Dörte Huscher, Katja Thiele, Erika Gromnica-Ihle, Gert Hein, Winfried Demary, Reiner Dreher, Angela Zink, and Frank Buttgereit: Dose-related patterns of glucocorticoid-induced side effects
Ann Rheum Dis Published Online First: 6 August 2008. doi:10.1136/ard.2008.092163 [Abstract] [Accepted Manuscript]

Katherine A. Guthrie, Natalia R Tishkevich, and J Lee Nelson: Non inherited maternal HLA antigens in susceptibility to familial rheumatoid arthritis
Ann Rheum Dis Published Online First: 6 August 2008. doi:10.1136/ard.2008.092312 [Abstract] [Accepted Manuscript]

4 August 2008

Michel Neidhart, Xenofon Baraliakos, Christian Seemayer, Caren Zelder, Renate E Gay, Beat A Michel, Heinrich Boehm, Steffen Gay, and Jürgen Braun: Expression of cathepsin K and MMP-1 indicate persistent osteodestruktive activity in longstanding ankylosing spondylitis
Ann Rheum Dis Published Online First: 4 August 2008. doi:10.1136/ard.2008.092494 [Abstract] [Accepted Manuscript]

Philip J Mease, Kathryn Hobbs, Andrew Chalmers, Hani El-Gabalawy, Arthur Bookman, Edward Keystone, Daniel E Furst, Pervin Anklesaria, and Alison E Heald: Local delivery of a recombinant adeno-associated vector containing a tumor necrosis factor- ${alpha}$ antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study
Ann Rheum Dis Published Online First: 4 August 2008. doi:10.1136/ard.2008.089375 [Abstract] [Accepted Manuscript]

Shun-Jen Chang, Ming-Hsien Tsai, Ying-Chin Ko, Pei-Chien Tsai, Chung-Jen Chen, and Han-Ming Lai: The cyclic GMP-dependent protein kinase II gene associates with gout disease identified by genome-wide analysis and case-control study
Ann Rheum Dis Published Online First: 4 August 2008. doi:10.1136/ard.2008.093252 [Abstract] [Accepted Manuscript]

3 August 2008

Miranda L Davies-Tuck, Anita E Wluka, Yuanyuan Wang, Dallas R English, Graham G Giles, and Flavia M. Cicuttini: The natural history of bone marrow lesions in community based adults with no clinical knee osteoarthritis
Ann Rheum Dis Published Online First: 3 August 2008. doi:10.1136/ard.2008.092973 [Abstract] [Accepted Manuscript]

Eamonn S Molloy, Carol A Langford, Tiffany M Clark, Carmen E Gota, and Gary S Hoffman: Anti-tumor necrosis factor therapy in patients with refractory Takayasu’s arteritis: long-term follow-up
Ann Rheum Dis Published Online First: 3 August 2008. doi:10.1136/ard.2008.093260 [Abstract] [Accepted Manuscript]

Tineke ACM van Geel, Svenhjalmar van Helden, Piet P Geusens, Bjorn Winkens, and Geert-Jan Dinant: Clinical subsequent fractures cluster in time after first fractures
Ann Rheum Dis Published Online First: 3 August 2008. doi:10.1136/ard.2008.092775 [Abstract] [Accepted Manuscript]

Antonios Stavropoulos-Kalinoglou, Giorgos S Metsios, Vasileios F Panoulas, Karen M J Douglas, Alan M Nevill, Athanasios Z Jamurtas, Marina Kita, Yiannis Koutedakis, and George D Kitas: Associations of obesity with modifiable risk factors for the development of cardiovascular disease in patients with rheumatoid arthritis
Ann Rheum Dis Published Online First: 3 August 2008. doi:10.1136/ard.2008.095596 [Abstract] [Accepted Manuscript]

2 August 2008

Gary J Macfarlane, Stephen R Pye, Joseph D Finn, Frederick CW Wu, Alan J Silman, Gyorgy Bartfai, Steven Boonen, Felipe Casaneuva, Gianni Forti, Aleksander Giwercman, Thang S Han, Iilpo T Huhtaniemi, Krzysztof Kula, Michael EJ Lean, Terence W O'Neill, Neil Pendleton, Margus Punab, and Dirk Vanderschueren: Investigating the determinants of international differences in the prevalence of chronic widespread pain: evidence from the European Male Ageing Study (EMAS)
Ann Rheum Dis Published Online First: 2 August 2008. doi:10.1136/ard.2008.089417 [Abstract] [Accepted Manuscript]

Janet Cushnaghan, James Bennett, Isabel Reading, Peter Croft, Patricia Byng, Ken Cox, Paul Dieppe, David Coggon, and Cyrus Cooper: Long-term outcome following total knee arthroplasty: a controlled longitudinal study
Ann Rheum Dis Published Online First: 2 August 2008. doi:10.1136/ard.2008.093229 [Abstract] [Accepted Manuscript]

Jacques Morel, Camille Roubille, Lourdes Planelles, Cecilia Rocha, Letiticia Fernandez, Cédric Lukas, Michael Hahne, and Bernard Combe: Serum levels of TNF family members APRIL and BLyS are inversely correlated in SLE
Ann Rheum Dis Published Online First: 2 August 2008. doi:10.1136/ard.2008.090928 [Abstract] [Accepted Manuscript]

29 July 2008

Peter A Merkel, David Curthbertson, Bernhard Hellmich, Gary S Hoffman, David Jayne, Cees GM Kallenberg, Jeffrey Krischer, Raashid Luqmani, Alfred Mahr, Eric L Matteson, Ulrich Specks, and John H Stone: Comparison of disease activity measures for ANCA-associated vasculitis
Ann Rheum Dis Published Online First: 29 July 2008. doi:10.1136/ard.2008.097758 [Abstract] [Accepted Manuscript]

Candice Trocmé, Hubert Marotte, Athan Baillet, Béatrice Pallot-Prades, Jérome Garin, Laurent Grange, Pierre Miossec, Jacques Tebib, François Berger, Michael J Nissen, Robert Juvin, Françoise Morel, and Philippe Gaudin: Apolipoprotein A-I and platelet factor 4 are biomarkers for Infliximab response in rheumatoid arthritis
Ann Rheum Dis Published Online First: 29 July 2008. doi:10.1136/ard.2008.093153 [Abstract] [Accepted Manuscript]

28 July 2008

Susan S Jick, Hyon Choi, Lin Li, Iain B McInnes, and Naveed Sattar: Hyperlipidemia, statin use and the risk of developing rheumatoid arthritis
Ann Rheum Dis Published Online First: 28 July 2008. doi:10.1136/ard.2008.091967 [Abstract] [Accepted Manuscript]

Taku Yatabe, Satsuki Mochizuki, Masayuki Takizawa, Miyuki Chijiiwa, Aiko Okada, Tokuhiro Kimura, Yoshinari Fujita, Hideo Matsumoto, Yoshiaki Toyama, and Yasunori Okada: Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes
Ann Rheum Dis Published Online First: 28 July 2008. doi:10.1136/ard.2007.086884 [Abstract] [Accepted Manuscript]

A MacIntyre, S W Brouilette, K J Lamb, K Radhakrishnan, L McGlynn, M M Chee, E K Parkinson, D Freeman, R Madhok, and P G Shiels: Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion
Ann Rheum Dis Published Online First: 28 July 2008. doi:10.1136/ard.2007.086652 [Abstract] [Accepted Manuscript]

M Rudwaleit, E Rødevand, P Holck, J Vanhoof, M Kron, S Kary, and H Kupper: Adalimumab effectively reduces the rate of anterior uveitis flares in patients with active ankylosing spondylitis: results of a prospective open-label study
Ann Rheum Dis Published Online First: 28 July 2008. doi:10.1136/ard.2008.092585 [Abstract] [Accepted Manuscript]

Sjoerd M Van Der Kooij, Yvonne PM Goekoop-Ruiterman, Jeska K De Vries-Bouwstra, Melek Guler-Yuksel, Aeilko H Zwinderman, Pit JSM Kerstens, Peter AHM Van Der Lubbe, Willem M De Beus, Bernard AM Grillet, Karel Ronday, Tom WJ Huizinga, Ferdinand C Breedveld, Ben AC Dijkmans, and Cornelia F Allaart: Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent onset rheumatoid arthritis
Ann Rheum Dis Published Online First: 28 July 2008. doi:10.1136/ard.2008.092254 [Abstract] [Accepted Manuscript]

24 July 2008

Maripat Corr, David L. Boyle, Lisa Ronacher, Nicole Flores, and Gary S Firestein: Synergistic benefit in inflammatory arthritis by targeting IKK ${epsilon}$ and IFN ${beta}$
Ann Rheum Dis Published Online First: 24 July 2008. doi:10.1136/ard.2008.095356 [Abstract] [Accepted Manuscript]

23 July 2008

Jean-Pierre Raynauld, Johanne Martel-Pelletier, Peter Bias, Stefan Laufer, Boulos Haraoui, Denis Choquette, André Beaulieu, François Abram, Marc Dorais, Eric Vignon, and Jean-Pierre Pelletier: Protective effects of licofelone, a 5-lipoxygenase and cyclooxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first Multi-Centre Clinical Trial using quantitative MRI
Ann Rheum Dis Published Online First: 23 July 2008. doi:10.1136/ard.2008.088732 [Abstract] [Accepted Manuscript]

Jörg HW Distler, Yannick Allanore, Jérôme Avouac, Roberto Giacomelli, Serena Guiducci, Falk Moritz, Alfiya Akhmetshina, Ulrich A. Walker, Armando Gabrielli, Ulf Müller-Ladner, Alan Tyndall, Marco Matucci-Cerinic, and Oliver Distler: EUSTAR statement and recommendations on endothelial precursor cells
Ann Rheum Dis Published Online First: 23 July 2008. doi:10.1136/ard.2008.091918 [Abstract] [Accepted Manuscript]

22 July 2008

U A Walker, A Tyndall, L Czirják, C P Denton, D Farge, O Kowal-Bielecka, U Müller-Ladner, and M Matucci-Cerinic: Geographic variation of disease manifestations in systemic sclerosis - a report from the EULAR Scleroderma Trials And Research (EUSTAR) group data base
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.091348 [Abstract] [Accepted Manuscript]

Arno WR van Kuijk, Danielle M Gerlag, Koen Vos, Gertjan Wolbink, Marjan de Groot, Menno A de Rie, A H Zwinderman, Ben AC Dijkmans, and Paul P Tak: A prospective, randomized, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: Effects of adalimumab treatment on synovial tissue
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.091389 [Abstract] [Accepted Manuscript]

Y K Onno Teng, E W Nivine Levarht, René EM Toes, Tom WJ Huizinga, and Jacob M van Laar: Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B-cell repopulation
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.092791 [Abstract] [Accepted Manuscript]

Jutta G. Richter, Arnd Becker, Tobias Koch, Mirco Nixdorf, Reinhart Willers, Robert Monser, Ben Schacher, Rieke Alten, Christof Specker, and Matthias Schneider: Patients' self-assessments via Tablet PC in routine patient care: comparison to standardized paper questionnaires
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.090209 [Abstract] [Accepted Manuscript]

A Zink, J Askling, W G Dixon, L Klareskog, A J Silman, and D PM Symmons: European Biologics Registers - Methodology, selected results, and perspectives
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.091926 [Abstract] [Accepted Manuscript]

Jade E Hollis-Moffatt, Marilyn E Merriman, Rachel A Rodger, Kerry A Rowley, Peter T Chapman, Nicola Dalbeth, Peter J Gow, Andrew A Harrison, John Highton, Peter BB Jones, John L O'Donnell, Lisa K Stamp, and Tony R Merriman: Evidence for association of an interleukin-23 receptor variant independent of the R381Q variant with rheumatoid arthritis
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.090142 [Abstract] [Accepted Manuscript]

Chiara Bocelli-Tyndall, Laura Bracci, Stefan Schaeren, Chantal Feder-Mengus, Andrea Barbero, Alan Tyndall, and Giulio C Spagnoli: Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated with the cytokines IL 2, IL 7 and IL 15
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.094003 [Abstract] [Accepted Manuscript]

Libin Zhang, Lorna B Jarvis, Han-Joo Baek, and J S Hill Gaston: Regulatory IL-4+CD8+ T cells in AS patients and healthy controls
Ann Rheum Dis Published Online First: 22 July 2008. doi:10.1136/ard.2008.088120 [Abstract] [Accepted Manuscript]

17 July 2008

Omri Snir, Mona Widhe, Caroline von Spee, Johan Lindberg, Leonid Padyukov, Karin Lundberg, Åke Engström, Patrick J Venables, Joakim Lundeberg, Rikard Holmdahl, Lars Klareskog, and Vivianne Malmström: Multiple antibody reactivities to citrullinated antigens in sera from rheumatoid arthritis patients – association with HLA-DRB1 alleles
Ann Rheum Dis Published Online First: 17 July 2008. doi:10.1136/ard.2008.091355 [Abstract] [Accepted Manuscript]

Mohammad B Nickdel, Paola Conigliaro, Guido Valesini, Sharon Hutchison, Robert Benson, Robert V Bundick, Andrew J Leishman, Iain B McInnes, James M Brewer, and Paul Garside: Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis
Ann Rheum Dis Published Online First: 17 July 2008. doi:10.1136/ard.2008.089300 [Abstract] [Accepted Manuscript]

Calin Popa, Lambertus J.H. van Tits, Pilar Barrera, Heidi L.M. Lemmers, Frank H.J. van den Hoogen, Piet L.C.M. van Riel, Timothy R.D.J. Radstake, Mihai G. Netea, Mark Roest, and Anton F.H. Stalenhoef: Anti-inflammatory therapy with TNF ${alpha}$ inhibitors improves HDL-cholesterol anti-oxidative capacity in rheumatoid arthritis patients
Ann Rheum Dis Published Online First: 17 July 2008. doi:10.1136/ard.2008.092171 [Abstract] [Accepted Manuscript]

16 July 2008

Andrew J Teichtahl, Anita E Wluka, Yuanyuan Wang, Fahad Hanna, Dallas R English, Graham G Giles, and Flavia M Cicuttini: Obesity and adiposity are associated with the rate of patella cartilage volume loss over two years in adults without knee osteoarthritis
Ann Rheum Dis Published Online First: 16 July 2008. doi:10.1136/ard.2008.093310 [Abstract] [Accepted Manuscript]

Berthold Hoppe, Thomas Häupl, Karl Egerer, Rudolf Gruber, Holger Kiesewetter, Abdulgabar Salama, Gerd R Burmester, and Thomas Dörner: Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis
Ann Rheum Dis Published Online First: 16 July 2008. doi:10.1136/ard.2008.091983 [Abstract] [Accepted Manuscript]

George E. Tzelepis, Georgia Kalliakosta, Athanasios G Tzioufas, Petros P. Sfikakis, Charalampos Mandros, Kyriaki A Boki, Charalampos Roussos, and Haralampos M. Moutsopoulos: Thoraco-abdominal motion in ankylosing spondylitis: association with standardized clinical measures and response to therapy
Ann Rheum Dis Published Online First: 16 July 2008. doi:10.1136/ard.2008.092650 [Abstract] [Accepted Manuscript]

M K Reinders, C Haagsma, T LThA Jansen, E N van Roon, J Delsing, M AFJ van de Laar, and J RBJ Brouwers: A randomised controlled trial on the efficacy and tolerability with dose-escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout
Ann Rheum Dis Published Online First: 16 July 2008. doi:10.1136/ard.2008.091462 [Abstract] [Accepted Manuscript]

Bernard Vandooren, Tineke Cantaert, Marie-José van Lierop, Ebo Bos, Leen De Rycke, Eric M Veys, Filip De Keyser, Barry Bresnihan, Frank P Luyten, Peter C Verdonk, Paul P Tak, Annemieke H Boots, and Dominique Baeten: Melanoma Inhibitory Activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis
Ann Rheum Dis Published Online First: 16 July 2008. doi:10.1136/ard.2007.085837 [Abstract] [Accepted Manuscript]