Background Increases in lipid levels and cancers with tofacitinib prompted a trial of major
adverse cardiovascular events (MACE) and cancers in patients with rheumatoid arthritis …

Background Cyclophosphamide and glucocorticoids have been the cornerstone of
remission-induction therapy for severe antineutrophil cytoplasmic antibody (ANCA)−associated …

Objective To develop and validate new classification criteria for adult and juvenile idiopathic
inflammatory myopathies (IIM) and their major subgroups. Methods Candidate variables …

Background The 18-month efficacy of a single course of rituximab as compared with conventional
immunosuppression with cyclophosphamide followed by azathioprine in patients with …

Rationale: Standard therapy for Wegener's granulomatosis is fraught with substantial toxicity
and not always effective. B lymphocytes have been implicated in the pathogenesis of …

Levels of interferon (IFN) were measured in 81 serum samples from 23 patients with systemic
lupus erythematosus (SLE) by a plaque‐reduction method and correlated retrospectively …

Objective This study was conducted to evaluate the efficacy and safety of repeated and
prolonged B cell depletion with rituximab (RTX) for the maintenance of long‐term remission in …

BACKGROUND: The pathogenic significance of antineutrophilic cytoplasmic antibodies (ANCA)
in Wegener’s granulomatosis is controversial. Their presence is influenced by the extent…

OBJECTIVES: To evaluate the utility of erythrocyte sedimentation rate (ESR) and C-reactive
protein (CRP) for the diagnosis of giant cell arteritis (GCA) and to determine the frequency of …

Objectives To evaluate incidence-trends and timing of large-vessel (LV) manifestations in
patients with giant cell arteritis (GCA), and to examine the influence of LV manifestations on …