Randomized double‐blind comparison of chimeric monoclonal antibody to tumor necrosis factor α (infliximab) versus placebo in active spondylarthropathy

…, D Baeten, A Herssens, F De Keyser… - Arthritis & …, 2002 - Wiley Online Library
Objective To confirm in a placebo‐controlled trial the safety and efficacy profile of infliximab
in short‐term treatment of patients with active spondylarthropathy (SpA). Methods Forty …

Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: diagnostic value, associations with radiological progression rate, and extra-articular …

…, L Boullart, G Serre, EM Veys, F De Keyser - Annals of the …, 2004 - ard.bmj.com
… F De Keyser1 … This work was supported by a grant from the ‘Vlaams instituut voor de
bevordering van het wetenschappelijk-technologisch onderzoek in de industrie’ (IWT/SB/11127) …

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

…, J Worthington, R Hesselstrand, V Smith, F de Keyser… - Nature …, 2010 - nature.com
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …

[HTML][HTML] Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis

…, LAB Joosten, V Smith, F de Keyser… - New England journal …, 2014 - Mass Medical Soc
Background Plasmacytoid dendritic cells have been implicated in the pathogenesis of
systemic sclerosis through mechanisms beyond the previously suggested production of type I …

Comparative study of the synovial histology in rheumatoid arthritis, spondyloarthropathy, and osteoarthritis: influence of disease duration and activity

…, H Mielants, EM Veys, F De Keyser - Annals of the …, 2000 - ard.bmj.com
OBJECTIVES To compare the macroscopic and microscopic characteristics of synovial
tissue in rheumatoid arthritis (RA), spondyloarthropathy (SpA), and osteoarthritis (OA) after …

Spondyloarthropathy is underestimated in inflammatory bowel disease: prevalence and HLA association.

…, F De Keyser, EM Veys, M De Vos - The Journal of …, 2000 - europepmc.org
Objective To determine the overall prevalence of spondyloarthropathy (SpA) among patients
with inflammatory bowel disease (IBD)[Crohn's disease (CD) and ulcerative colitis (UC)]. …

[HTML][HTML] Synovial histopathology of psoriatic arthritis, both oligo-and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis

…, JD Cañete, AM Boots, EM Veys, F De Keyser - Arthritis research & …, 2005 - Springer
At present only few biological data are available to indicate whether psoriatic arthritis (PsA)
is part of the spondyloarthropathy (SpA) concept, whether it is a separate disease entity or a …

[HTML][HTML] The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for …

H Brahms, J Raymackers, A Union, F De Keyser… - Journal of Biological …, 2000 - ASBMB
The Sm proteins B/B′, D1, D2, D3, E, F, and G are components of the small nuclear
ribonucleoproteins U1, U2, U4/U6, and U5 that are essential for the splicing of pre-mRNAs in …

Effects of a loading dose regimen of three infusions of chimeric monoclonal antibody to tumour necrosis factor α (infliximab) in spondyloarthropathy: an open pilot …

…, E Kruithof, D Baeten, F De Keyser… - Annals of the …, 2000 - ard.bmj.com
OBJECTIVE To evaluate the efficacy and safety of a loading dose regimen of three
intravenous infusions with infliximab in patients with active spondyloarthropathy. METHODS A …

Crohn's disease associated with spondyloarthropathy: effect of TNF-α blockade with infliximab on articular symptoms

F Van den Bosch, E Kruithof, M De Vos, F De Keyser… - The Lancet, 2000 - thelancet.com
Four patients with Crohn's disease and spondyloarthropathy were treated with infliximab for
treatment-resistant gut inflammation. A substantial improvement in gastrointestinal signs and …