[HTML][HTML] The mammalian gene function resource: the International Knockout Mouse Consortium

…, D Valenzuela, AP West, K Yamamura, Y Yoshinaga… - Mammalian …, 2012 - Springer
Abstract In 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious
promise to generate mutations in virtually every protein-coding gene of the mouse genome …

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

…, BA Hosler, P Cortelli, PJ De Jong, Y Yoshinaga… - Science, 2009 - science.org
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disorder. Ten
percent of cases are inherited; most involve unidentified genes. We report here 13 mutations …

[HTML][HTML] Comparative and demographic analysis of orang-utan genomes

…, A Hobolth, MH Schierup, OA Ryder, Y Yoshinaga… - Nature, 2011 - nature.com
Abstract 'Orang-utan'is derived from a Malay term meaning 'man of the forest'and aptly
describes the southeast Asian great apes native to Sumatra and Borneo. The orang-utan …

[HTML][HTML] Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

…, J Lynch, P Watson, M Jansen, Y Yoshinaga… - Cell, 2007 - cell.com
The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no
predisposing mutation has been convincingly identified. We show that loss or reduced …

[HTML][HTML] Genomic mechanisms of climate adaptation in polyploid bioenergy switchgrass

…, J Webber, X Weng, M Williams, GA Wu, Y Yoshinaga… - Nature, 2021 - nature.com
Long-term climate change and periodic environmental extremes threaten food and fuel
security and global crop productivity,–. Although molecular and adaptive breeding strategies …

[PDF][PDF] High-throughput single-cell transcriptome profiling of plant cell types

CN Shulse, BJ Cole, D Ciobanu, J Lin, Y Yoshinaga… - Cell reports, 2019 - cell.com
Single-cell transcriptome profiling of heterogeneous tissues can provide high-resolution
windows into developmental dynamics and environmental responses, but its application to …

A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter

…, H Ayyub, RJ Gibbons, D Vernimmen, Y Yoshinaga… - Science, 2006 - science.org
We describe a pathogenetic mechanism underlying a variant form of the inherited blood
disorder α thalassemia. Association studies of affected individuals from Melanesia localized …

Hydrogenation of nitrate in water to nitrogen over Pd–Cu supported on active carbon

Y Yoshinaga, T Akita, I Mikami, T Okuhara - Journal of catalysis, 2002 - Elsevier
Catalytic removal of nitrate in water by hydrogenation was investigated by using supported
Pd–Cu catalysts at 333 K in a flow system. Active carbon (AC) was superior in conversion …

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

…, S Chang, Y Tu, RH Barnes, Y Yoshinaga… - Molecular biology of …, 2011 - Am Soc Cell Biol
Neuronal migration is essential for the development of the mammalian brain. Here, we
document severe defects in neuronal migration and reduced numbers of neurons in lamin …

Comparative genomics of early-diverging mushroom-forming fungi provides insights into the origins of lignocellulose decay capabilities

…, T Shirouzu, Y Yoshinaga… - Molecular biology …, 2016 - academic.oup.com
Evolution of lignocellulose decomposition was one of the most ecologically important
innovations in fungi. White-rot fungi in the Agaricomycetes (mushrooms and relatives) are …