In silico vaccine strain prediction for human influenza viruses
TR Klingen, S Reimering, CA Guzmán… - Trends in microbiology, 2018 - cell.com
Vaccines preventing seasonal influenza infections save many lives every year; however,
due to rapid viral evolution, they have to be updated frequently to remain effective. To …
due to rapid viral evolution, they have to be updated frequently to remain effective. To …
Secondary breast cancer: a 5‐year population‐based study with review of the literature
TA Klingen, H Klaasen, H Aas, Y Chen, LA Akslen - Apmis, 2009 - Wiley Online Library
Secondary tumours in the breast are rare. Based on literature, an incidence of 0.4–2% is
reported. In this population‐based study, secondary breast tumours from a 5‐year period …
reported. In this population‐based study, secondary breast tumours from a 5‐year period …
Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer
Tumor-associated macrophages (TAM) resemble M2 macrophages, promote tumor invasion
and show strong expression of CD163 in breast cancer. We here investigated the …
and show strong expression of CD163 in breast cancer. We here investigated the …
Full-field digital mammography compared to screen film mammography in the prevalent round of a population-based screening programme: the Vestfold County Study
E Vigeland, H Klaasen, TA Klingen, S Hofvind… - European …, 2008 - Springer
The purpose of the study was to compare the performance of full-field digital mammography
(FFDM) with soft-copy reading to screen film mammography (SFM) used during the first …
(FFDM) with soft-copy reading to screen film mammography (SFM) used during the first …
[HTML][HTML] Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
TA Klingen, Y Chen, MD Gundersen, H Aas… - Diagnostic …, 2010 - Springer
This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1)
positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal …
positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal …
Computational prediction of vaccine strains for human influenza A (H3N2) viruses
L Steinbrück, TR Klingen, AC McHardy - Journal of virology, 2014 - Am Soc Microbiol
Human influenza A viruses are rapidly evolving pathogens that cause substantial morbidity
and mortality in seasonal epidemics around the globe. To ensure continued protection, the …
and mortality in seasonal epidemics around the globe. To ensure continued protection, the …
[HTML][HTML] Evolution of 2009 H1N1 influenza viruses during the pandemic correlates with increased viral pathogenicity and transmissibility in the ferret model
A Otte, AC Marriott, C Dreier, B Dove, K Mooren… - Scientific reports, 2016 - nature.com
There is increasing evidence that 2009 pandemic H1N1 influenza viruses have evolved
after pandemic onset giving rise to severe epidemics in subsequent waves. However, it still …
after pandemic onset giving rise to severe epidemics in subsequent waves. However, it still …
[HTML][HTML] Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer
K Krüger, E Wik, G Knutsvik, H Nalwoga, TA Klingen… - Scientific reports, 2017 - nature.com
We here examined whether Nestin, by protein and mRNA levels, could be a predictor of
BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours …
BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours …
[HTML][HTML] Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based …
Y Chen, TA Klingen, E Wik, H Aas, E Vigeland… - Diagnostic …, 2014 - Springer
Background Mammography screen-detected breast cancers have a better prognosis than
predicted from established prognostic markers. A search for additional features that are …
predicted from established prognostic markers. A search for additional features that are …
[HTML][HTML] Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer
S Aziz, E Wik, G Knutsvik, TA Klingen, Y Chen… - PLoS …, 2017 - journals.plos.org
Presence of lymph node (LN) metastasis is a strong prognostic factor in breast cancer,
whereas the importance of extra-nodal extension and other nodal tumor features have not …
whereas the importance of extra-nodal extension and other nodal tumor features have not …