The vitamin D receptor (VDR), a member of the nuclear receptor superfamily of
transcriptional regulators, is crucial to calcitriol signalling. VDR is regulated by genetic and …

Silicone oil (SO) still represents the main choice for long‐term intraocular tamponade in
complicated vitreoretinal surgery. This review compared the complications associated with …

Bone is crucial for the support of muscles and the protection of vital organs, and as a
reservoir of calcium and phosphorus. Bone is one of the most metabolically active tissues …

Age-related macular degeneration (AMD) is a complex, multifactorial and progressive retinal
disease affecting millions of people worldwide. In developed countries, it is the leading …

Retinal photoreceptor degeneration occurs frequently in several neurodegenerative retinal
diseases such as age-related macular degeneration, retinitis pigmentosa, or genetic retinal …

Paget disease of bone (PDB) is a focal bone disorder affecting the skeleton segmentally.
The main alteration resides in osteoclasts that increase in size, number and activity. Many …

Over 175 pathogenic mutations in the Peripherin-2 (PRPH2) gene are linked to various
retinal diseases. We report the phenotype and genotype of eight families (24 patients) with …

Retinal degenerations are the leading causes of irreversible visual loss worldwide. Many
pathologies included under this umbrella involve progressive degeneration and ultimate …

Diabetic macular oedema (DMO) is one of the leading causes of vision loss associated with
diabetic retinopathy (DR). New insights in managing this condition have changed the …

Calcifediol (25-OH-vitamin D3) is the prohormone of the vitamin D endocrine system. It is
used to prevent and treat vitamin D deficiency. Calcifediol, as well as cholecalciferol (vitamin …