Background Immunotherapy is a firmly established pillar in the treatment of cancer,
alongside the traditional approaches of surgery, radiotherapy, and chemotherapy. Like …

Age is the most important risk factor for the development of infectious diseases, cancer and
chronic inflammatory diseases including rheumatoid arthritis (RA). The very act of living …

Objective Several lines of evidence indicate that B cells may be involved in the
immunopathology of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR). This study …

Presence of autoantibodies precedes development of seropositive rheumatoid arthritis (SP
RA) and seropositive arthralgia patients (SAP) are at risk of developing RA. The aims of the …

Objective. The role of natural killer (NK) cells in the immunopathogenesis of rheumatoid
arthritis (RA) is unclear. Therefore, numerical and functional alterations of CD56dim and …

Papillary thyroid cancer (PTC) often co-occurs with Hashimoto's thyroiditis, an association
that has long been reported in clinical studies yet remains controversial. Some studies, in …

Improved understanding of the immune events discriminating between seropositive
arthralgia and clinical synovitis is of key importance in rheumatology research. Ample …

Autoimmune hypophysitis is classified as primary if its origin is idiopathic and secondary if it
develops as a consequence of treatment with immune checkpoint inhibitors. Expanding use …

Abstract Objective. CD70-expressing CD4 T cells are enriched in RA and promote
autoimmunity via co-stimulatory CD70-CD27 interaction. This study aimed to explore the …

Objective Seropositive arthralgia patients (SAP) are at high risk of developing rheumatoid
arthritis (RA). This prospective study aimed to determine whether altered peripheral …