We performed a systematic literature review to summarize the underlying pathogenic
mechanisms by which adipokines influence rheumatological diseases and the resulting …

Pulmonary arterial hypertension (PAH) represents one of the main clinical expressions of
the vascular changes in systemic sclerosis (SSc). Lung microvascular changes can play a …

Nailfold video-capillaroscopy (NVC) is a useful diagnostic tool, used to early detect
abnormalities in micro-circulation, providing a qualitative description of microvascular …

Background: Tofacitinib (TOFA) was the first Janus kinase inhibitor (JAKi) to be approved for
the treatment of rheumatoid arthritis (RA). However, data on the retention rate of TOFA …

Pfeifer-Weber-Christian disease (PWCD) is a rare idiopathic disease characterized by
lobular panniculitis of adipose tissue with systemic symptoms and multiple organ …

Aim Endothelial dysfunction represents a key feature of the pathological process underlying
micro and macro-vascular damage in Systemic Sclerosis (SSc). This study aims to improve …

Introduction: Enthesitis and dactylitis are difficult-to-treat features of psoriatic arthritis (PsA),
leading to disability and affecting quality of life. Objective: The aim of this study is to evaluate …

Background: To date, only a few real-world-setting studies evaluated apremilast
effectiveness in psoriatic arthritis (PsA). The aims of this retrospective observational study …

Background: To date, only a few real-world-setting studies evaluated apremilast
effectiveness in psoriatic arthritis (PsA). The aims of this retrospective observational study …

Background Psoriatic arthritis (PsA) is an inflammatory rheumatic disease characterized by
different phenotypes in terms of joint involvement. Apremilast, PDE4 competitive inhibitor …