The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

MicroRNAs (miRNAs) are endogenously encoded∼ 22 nt small non‐coding RNAs. They
function as key players of many cellular processes by base pairing with target mRNAs and …

Patients with kidney failure are at increased risk of SARS-CoV-2 infection, making effective
vaccinations a critical need. It is not known how well mRNA vaccines induce B and plasma …

Why do we still have no cure for chronic inflammatory diseases? One reason could be that
current therapies are based on the assumption that chronic inflammation is driven by …

The pathogenesis of severe COVID-19 reflects an inefficient immune reaction to SARS-CoV-
2. Here we analyze, at the single cell level, plasmablasts egressed into the blood to study …

After being activated by antigen, helper T lymphocytes switch from a resting state to clonal
expansion. This switch requires inactivation of the transcription factor Foxo1, a suppressor of …

Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

The co-stimulators ICOS (inducible T cell co-stimulator) and CD28 are both important for T
follicular helper (TFH) cells, yet their individual contributions are unclear. Here, we show that …

Clonal expansion of cells with somatically diversified receptors and their long-term
maintenance as memory cells is a hallmark of adaptive immunity. Here, we studied …

Although T helper 17 (TH17) cells have been acknowledged as crucial mediators of
autoimmune tissue damage, the effector cytokines responsible for their pathogenicity still …