User profiles for "author:M. Horwitz"

Marcus A. Horwitz

Professor of Medicine and Microbiology, Immunology & Molecular Genetics
Verified email at mednet.ucla.edu
Cited by 25232

Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases

B Korkmaz, MS Horwitz, DE Jenne, F Gauthier - Pharmacological reviews, 2010 - ASPET
Polymorphonuclear neutrophils are the first cells recruited to inflammatory sites and form the
earliest line of defense against invading microorganisms. Neutrophil elastase, proteinase 3 …

The impact of adenovirus infection on the immunocompromised host

T Kojaoghlanian, P Flomenberg… - Reviews in medical …, 2003 - Wiley Online Library
Adenovirus (Ad) infections in immunocompromised hosts have increased in frequency as
the number of patients with transplants of bone marrow, liver, kidney, heart and other organs …

Neutrophil elastase in cyclic and severe congenital neutropenia

MS Horwitz, Z Duan, B Korkmaz, HH Lee, ME Mealiffe… - Blood, 2007 - ashpublications.org
Mutations in ELA2 encoding the neutrophil granule protease, neutrophil elastase (NE), are
the major cause of the 2 main forms of hereditary neutropenia, cyclic neutropenia and …

Foreign language classroom anxiety

EK Horwitz, MB Horwitz, J Cope - The Modern language journal, 1986 - JSTOR
Such statements are all too familiar to teachers of foreign languages. Many people claim to
have a mental block against learning a foreign language, although these same people may …

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

JM Bergelson, JA Cunningham, G Droguett… - Science, 1997 - science.org
A complementary DNA clone has been isolated that encodes a coxsackievirus and
adenovirus receptor (CAR). When transfected with CAR complementary DNA …

[BOOK][B] The transformation of American law, 1870-1960: The crisis of legal orthodoxy

MJ Horwitz - 1992 - books.google.com
When the first volume of Morton Horwitz's monumental history of American law appeared in
1977, it was universally acclaimed as one of the most significant works ever published in …

Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

P Borrow, H Lewicki, X Wei, MS Horwitz, N Peffer… - Nature medicine, 1997 - nature.com
The HIV-1-specific cytotoxic T lymphocyte (CTL) response is temporally associated with the
decline in viremia during primary HIV-1 infection, but definitive evidence that it is of …

Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

MS Horwitz, LM Bradley, J Harbertson, T Krahl, J Lee… - Nature medicine, 1998 - nature.com
Viral induction of autoimmunity is thought to occur by either bystander T-cell activation or
molecular mimicry. Coxsackie B4 virus is strongly associated with the development of insulin …

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

DL Clemens, MA Horwitz - The Journal of experimental medicine, 1995 - rupress.org
We have used the cryosection immunogold technique to study the composition of the
Mycobacterium tuberculosis phagosome. We have used quantitative immunogold staining to …

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

CN Hahn, CE Chong, CL Carmichael, EJ Wilkins… - Nature …, 2011 - nature.com
We report the discovery of GATA2 as a new myelodysplastic syndrome (MDS)-acute myeloid
leukemia (AML) predisposition gene. We found the same, previously unidentified …