Objectives To develop recommendations for the diagnosis, prevention and treatment of
neuropsychiatric systemic lupus erythematosus (NPSLE) manifestations. Methods The …

The inflammatory myopathies, commonly described as idiopathic, are the largest group of
acquired and potentially treatable myopathies. On the basis of unique clinical …

THE polymyositis and dermatomyositis complex encompasses a heterogeneous group of
acquired muscle diseases called inflammatory myopathies because muscle weakness and …

Background Dermatomyositis is a clinically distinct myopathy characterized by rash and a
complement-mediated microangiopathy that results in the destruction of muscle fibers. In …

Both infection with the human immunodeficiency virus type 1 (HIV) and zidovudine (formerly
called azidothymidine [AZT]) cause myopathy. To identify criteria for distinguishing …

Long-term zidovudine therapy in patients with human immunodeficiency virus (HIV) infection
can cause a destructive mitochondrial myopathy with histological features of ragged-red …

Long-term treatment with antiviral nucleoside analogue drugs, such as AZT, can give rise to
delayed and at times severe mitochondrial toxicity. Although these toxic effects are manifest …

Inflammatory Muscle Diseases | NEJM Skip to main content NEJM Group Follow Us Facebook
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A New Approach to the Classification of Idiopathic Inflammat... : Medicine A New Approach to
the Classification of Idiopathic Inflammatory Myopathy: Myositis-Specific Autoantibodies Define …

This multicenter, randomized, double‐blind, crossover trial compared a 6 week course of
oral prednisolone tapering from 60 mg to 10 mg daily with intravenous immunoglobulin …