Inflammation, growth factors, and pulmonary vascular remodeling

PM Hassoun, L Mouthon, JA Barberą… - Journal of the american …, 2009 - jacc.org
Inflammatory processes are prominent in various types of human and experimental
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …

Self-reactive antibodies (natural autoantibodies) in healthy individuals

S Lacroix-Desmazes, SV Kaveri, L Mouthon… - Journal of …, 1998 - Elsevier
Antibodies that are present in the serum of healthy individuals in the absence of deliberate
immunization with any antigen, are refered to as natural antibodies. A vast majority of natural …

[HTML][HTML] Intravenous immunoglobulin: an update on the clinical use and mechanisms of action

…, S Siberil, S Graff-Dubois, LUC Mouthon… - Journal of clinical …, 2007 - Springer
Initially used as a replacement therapy for immunodeficiency diseases, intravenous
immunoglobulin (IVIg) is now widely used for a number of autoimmune and inflammatory …

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

J Hadjadj, N Yatim, L Barnabei, A Corneau, J Boussier… - Science, 2020 - science.org
Coronavirus disease 2019 (COVID-19) is characterized by distinct patterns of disease
progression that suggest diverse host immune responses. We performed an integrated …

[PDF][PDF] Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

A Silvin, N Chapuis, G Dunsmore, AG Goubet… - Cell, 2020 - cell.com
Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19),
caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with …

[HTML][HTML] Rituximab versus azathioprine for maintenance in ANCA-associated vasculitis

L Guillevin, C Pagnoux, A Karras… - … England Journal of …, 2014 - Mass Medical Soc
Background The combination of cyclophosphamide and glucocorticoids leads to remission
in most patients with antineutrophil cytoplasm antibody (ANCA)–associated vasculitides …

[HTML][HTML] Serum neutralization of SARS-CoV-2 Omicron sublineages BA. 1 and BA. 2 in patients receiving monoclonal antibodies

T Bruel, J Hadjadj, P Maes, D Planas, A Seve… - Nature medicine, 2022 - nature.com
The severe acute respiratory syndrome coronavirus 2 Omicron BA. 1 sublineage has been
supplanted in many countries by the BA. 2 sublineage. BA. 2 differs from BA. 1 by about 21 …

Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study

E Hachulla, V Gressin, L Guillevin… - Arthritis & …, 2005 - Wiley Online Library
Objective Screening allows for early management of pulmonary arterial hypertension (PAH),
a severe complication of systemic sclerosis (SSc). Since no consensus has been reached …

The Five-Factor Score revisited: assessment of prognoses of systemic necrotizing vasculitides based on the French Vasculitis Study Group (FVSG) cohort

L Guillevin, C Pagnoux, R Seror, A Mahr, L Mouthon… - Medicine, 2011 - journals.lww.com
Abstract The 1996 Five-Factor Score (FFS) for systemic necrotizing vasculitides (polyarteritis
nodosa [PAN], microscopic polyangiitis [MPA], and Churg-Strauss syndrome [CSS]) is used …

Eosinophilic granulomatosis with polyangiitis (Churg‐Strauss): clinical characteristics and long‐term followup of the 383 patients enrolled in the French Vasculitis …

C Comarmond, C Pagnoux, M Khellaf… - Arthritis & …, 2013 - Wiley Online Library
Objective Earlier studies of eosinophilic granulomatosis with polyangiitis (Churg‐
Strauss)(EGPA), with limited patient numbers and followup durations, demonstrated that …