[HTML][HTML] Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
MC Zillikens, S Demissie, YH Hsu… - Nature …, 2017 - nature.com
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We
performed a genome-wide association study for whole body (20 cohorts of European …
performed a genome-wide association study for whole body (20 cohorts of European …
[HTML][HTML] Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures
NR Jørgensen, LB Husted, KK Skarratt… - European Journal of …, 2012 - nature.com
The purinergic P2X7 receptor has a major role in the regulation of osteoblast and osteoclast
activity and changes in receptor function may therefore affect bone mass in vivo. The aim of …
activity and changes in receptor function may therefore affect bone mass in vivo. The aim of …
The structure of bovine complement component 3 reveals the basis for thioester function
F Fredslund, L Jenner, LB Husted, J Nyborg… - Journal of molecular …, 2006 - Elsevier
The third component of complement (C3) is a 190 kDa glycoprotein essential for eliciting the
complement response. The protein consists of two polypeptide chains (α and β) held …
complement response. The protein consists of two polypeptide chains (α and β) held …
[HTML][HTML] Disentangling the genetics of lean mass
Background Lean body mass (LM) plays an important role in mobility and metabolic
function. We previously identified five loci associated with LM adjusted for fat mass in …
function. We previously identified five loci associated with LM adjusted for fat mass in …
Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus
Vertebral fracture risk is a heritable complex trait. The aim of this study was to identify
genetic susceptibility factors for osteoporotic vertebral fractures applying a genome-wide …
genetic susceptibility factors for osteoporotic vertebral fractures applying a genome-wide …
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density
Objectives To identify genetic determinants of susceptibility to clinical vertebral fractures,
which is an important complication of osteoporosis. Methods Here we conduct a genome …
which is an important complication of osteoporosis. Methods Here we conduct a genome …
[HTML][HTML] Localization of Carbohydrate Attachment Sites and Disulfide Bridges in Limulus α2-Macroglobulin: EVIDENCE FOR TWO FORMS DIFFERING PRIMARILY IN …
LB Husted, ES Sørensen, PB Armstrong… - Journal of Biological …, 2002 - ASBMB
The primary structure determination of the dimeric invertebrate α 2-macroglobulin (α 2 M)
from Limulus polyphemus has been completed by determining its sites of glycosylation and …
from Limulus polyphemus has been completed by determining its sites of glycosylation and …
Localisation of the major reactive lysine residue involved in the selfcrosslinking of proteinase-activated Limulus α2-macroglobulin
K Dolmer, LB Husted, PB Armstrong, L Sottrup-Jensen - FEBS letters, 1996 - Elsevier
When α2-macroglobulin (α2M) from the American horseshoe crab, Limulus polyphemus,
reacts with proteinases, its thiol esters, like those of other α-macroglobulins, become …
reacts with proteinases, its thiol esters, like those of other α-macroglobulins, become …
4-(Aminosulfonyl)-7-fluoro-2, 1, 3-benzoxadiazole is not specific for labeling of sulfhydryl groups in proteins as it may also react with phenolic hydroxyl groups and …
LB Husted, ES Sørensen… - Analytical …, 2003 - pubmed.ncbi.nlm.nih.gov
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole is not specific for labeling of sulfhydryl
groups in proteins as it may also react with phenolic hydroxyl groups and amino groups 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole …
groups in proteins as it may also react with phenolic hydroxyl groups and amino groups 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole …
Supplementary data Identification of a novel locus on chromosome 2q13 which predisposes to clinical vertebral fractures independently of bone density
The case definition of clinical vertebral fractures for all cohorts was that the patient had
presented to primary or secondary care with symptoms of acute or chronic back pain, height …
presented to primary or secondary care with symptoms of acute or chronic back pain, height …