User profiles for "author:J. Calvo"
Juan R. CalvoUniversidad de Sevilla Verified email at us.es Cited by 11451 |
Balancing repair and tolerance of DNA damage caused by alkylating agents
Alkylating agents constitute a major class of frontline chemotherapeutic drugs that inflict
cytotoxic DNA damage as their main mode of action, in addition to collateral mutagenic …
cytotoxic DNA damage as their main mode of action, in addition to collateral mutagenic …
Significance of melatonin in antioxidative defense system: reactions and products
Melatonin is a potent endogenous free radical scavenger, actions that are independent of its
many receptor-mediated effects. In the last several years, hundreds of publications have …
many receptor-mediated effects. In the last several years, hundreds of publications have …
Melatonin and its relation to the immune system and inflammation
Melatonin (N‐acetyl‐5‐methoxytryptamine) was initially thought to be produced exclusively
in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for …
in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for …
Replication fork stability confers chemoresistance in BRCA-deficient cells
A Ray Chaudhuri, E Callen, X Ding, E Gogola… - Nature, 2016 - nature.com
Cells deficient in the Brca1 and Brca2 genes have reduced capacity to repair DNA double-
strand breaks by homologous recombination and consequently are hypersensitive to DNA …
strand breaks by homologous recombination and consequently are hypersensitive to DNA …
A large family of bacterial activator proteins.
S Henikoff, GW Haughn, JM Calvo… - Proceedings of the …, 1988 - National Acad Sciences
At least nine different bacterial proteins belong to the LysR family. The gene sequence for
one of these proteins is presented here. Six others (Escherichia coli LysR, IlvY, CysB; …
one of these proteins is presented here. Six others (Escherichia coli LysR, IlvY, CysB; …
Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance
It has been historically assumed that the pineal gland is the major source of melatonin (N‐
acetyl‐5‐methoxytryptamine) in vertebrates. Melatonin plays a central role in fine‐tuning …
acetyl‐5‐methoxytryptamine) in vertebrates. Melatonin plays a central role in fine‐tuning …
[PDF][PDF] Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
…, PS VanderVere-Carozza, KS Pawelczak, J Calvo… - Molecular cell, 2021 - cell.com
Mutations in BRCA1 or BRCA2 (BRCA) is synthetic lethal with poly (ADP-ribose)
polymerase inhibitors (PARPi). Lethality is thought to derive from DNA double-stranded …
polymerase inhibitors (PARPi). Lethality is thought to derive from DNA double-stranded …
Steps of membrane blocking in flux decline during protein microfiltration
WR Bowen, JI Calvo, A Hernandez - Journal of Membrane Science, 1995 - Elsevier
The flow decline is studied in typical experiments with dead-end microfiltration of BSA
solutions (1 and 0.1 kg/m3) through Cyclopore® track-etched polycarbonate membranes …
solutions (1 and 0.1 kg/m3) through Cyclopore® track-etched polycarbonate membranes …
Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type …
S Garcia-Mauriño, MG Gonzalez-Haba… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
This paper shows that melatonin is able to activate human Th1 lymphocytes by increasing
the production of IL-2 and IFN-gamma in vitro. Th2 cells appear not to be affected by …
the production of IL-2 and IFN-gamma in vitro. Th2 cells appear not to be affected by …
[HTML][HTML] Evolution of titanosaurid sauropods: Phytogenetic analysis based on the postcranial evidence.
L Salgado, RA Coria, JO Calvo - Ameghiniana, 1997 - books.google.com
Evolution of titanosaurid sauropods: Phytogenetic analysis based on the postcranial evidence.
Page 5 AMEGHINIANA (Rev. Asoc. Paleontol. Argent.) ISSN 0002-70l4 34 (l): 3-32. Buenos …
Page 5 AMEGHINIANA (Rev. Asoc. Paleontol. Argent.) ISSN 0002-70l4 34 (l): 3-32. Buenos …