The effect of hydrophilic coatings on the uptake of colloidal particles by the liver and by peritoneal macrophages

L Ilium, IM Hunneyball, SS Davis - International journal of pharmaceutics, 1986 - Elsevier
By coating polystyrene microspheres (60 nm in diameter) with hydrophilic materials such as
secretory immunoglobulin A (SIgA), egg lecithin and non-ionic surfactants (poloxamer 188 …

Preparation and evaluation of biodegradable polymeric systems for the intra-articular delivery of drugs

JH Ratcliffe, IM Hunneyball, A Smith… - Journal of pharmacy …, 1984 - academic.oup.com
Colloidal suspensions of four biodegradable polymers, polylactic acid (PLA),
polybutylcyanoacrylate (PBCA), gelatin (PG) and albumin (PA) were prepared within the …

Albumin microspheres for intra‐articular drug delivery: Investigation of their retention in normal and arthritic knee joints of rabbits

JH Ratcliffe, IM Hunneyball, CG Wilson… - Journal of pharmacy …, 1987 - Wiley Online Library
The retention of 131I‐labelled albumin microspheres and microsphere‐entrapped [131I]
rose bengal was investigated in normal and experimentally arthritic knee joints of rabbits …

Treatment of elderly primary insomnia patients with EVT 201 improves sleep initiation, sleep maintenance, and daytime sleepiness

JK Walsh, L Salkeld, LJ Knowles, T Tasker… - Sleep Medicine, 2010 - Elsevier
OBJECTIVE: Two doses of EVT 201, a partial positive allosteric modulator of the GABAA
system, were evaluated in elderly primary insomnia patients with daytime sleepiness …

Recent advances in the use of microspheres for targeted therapy.

SS Davis, IM Hunneyball, L Illum… - … and clinical research, 1985 - europepmc.org
In recent years the concept of using small colloidal particles for the selective delivery of
drugs has been explored experimentally using a variety of different physical systems (for …

Inflammatory involvement in rabbit knee following immobilization and resulting in osteoarthritis

JE Michelsson, IM Hunneyball - Scandinavian journal of …, 1984 - Taylor & Francis
The inflammatory involvement of the synovium in immobilization-induced experimental
osteoarthritis in rabbit knees has been investigated. One knee of each of 33 rabbits was …

The partial positive allosteric GABAA receptor modulator EVT 201 is efficacious and safe in the treatment of adult primary insomnia patients

JK Walsh, S Thacker, LJ Knowles, T Tasker… - Sleep Medicine, 2009 - Elsevier
Objective: To evaluate polysomnographic (PSG) and self-reported measures of efficacy and
the safety of EVT 201 in patients with primary insomnia. Patients and methods: Following …

Pharmacological studies of antigen-induced arthritis in BALB/c mice I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory …

IM Hunneyball, MJ Crossley, M Spowage - Agents and Actions, 1986 - Springer
Chronic monoarticular allergic arthritis was induced in BALB/c mice using methylated BSA
as antigen and Freund's complete adjuvant, together with Bordetella pertussis as a …

Recent developments in disease-modifying antirheumatic drugs

B Berde, CJ Cavallito, IM Hunneyball, S Sharma… - Progress in Drug …, 1980 - Springer
Drugs used for the treatment of rheumatoid arthritis may be subdivided into two groups: first
the non-steroidal anti-inflammatory agents (NSAIA) of the aspirin type, which suppress acute …

Chemotherapy of cestode infections

B Berde, CJ Cavallito, IM Hunneyball, S Sharma… - Progress in Drug …, 1980 - Springer
The cestode infections are one of the most common intestinal parasitic diseases responsible
for several health hazards in man and animals all over the world. Surprisingly, the …