User profiles for "author:Hani El-Gabalawy"
Hani El-GabalawyProfessor of Medicine and Immunology, University of Manitoba Verified email at umanitoba.ca Cited by 15434 |
[HTML][HTML] Oxidation in rheumatoid arthritis
CA Hitchon, HS El-Gabalawy - Arthritis Res Ther, 2004 - Springer
Oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis.
Reactive oxygen species (ROS) produced in the course of cellular oxidative …
Reactive oxygen species (ROS) produced in the course of cellular oxidative …
Epidemiology of immune-mediated inflammatory diseases: incidence, prevalence, natural history, and comorbidities
H El-Gabalawy, LC Guenther… - The Journal of …, 2010 - jrheum.org
Immune-mediated inflammatory diseases (IMID) present a group of common and highly
disabling chronic conditions that share inflammatory pathways. Several incidence and …
disabling chronic conditions that share inflammatory pathways. Several incidence and …
[HTML][HTML] Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE
KD Deane, H El-Gabalawy - Nature Reviews Rheumatology, 2014 - nature.com
Established and emerging data demonstrate that a'preclinical'period of disease precedes
the onset of clinical rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), as …
the onset of clinical rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), as …
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis
V Groh, A Brühl, H El-Gabalawy… - Proceedings of the …, 2003 - National Acad Sciences
Effector T cell responses can be modulated by competing positive or negative signals
transduced by natural killer (NK) cell receptors. This raises the possibility that dominant T …
transduced by natural killer (NK) cell receptors. This raises the possibility that dominant T …
Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+ T cell accumulation in rheumatoid arthritis synovium
T Nanki, K Hayashida, HS El-Gabalawy… - The Journal of …, 2000 - journals.aai.org
Rheumatoid arthritis (RA) is characterized by the accumulation of CD4+ memory T cells in
the inflamed synovium. To address the mechanism, we analyzed chemokine receptor …
the inflamed synovium. To address the mechanism, we analyzed chemokine receptor …
[HTML][HTML] Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
R Goldbach-Mansky, J Lee, A McCoy… - Arthritis Research & …, 2000 - Springer
Statement of findings An inception cohort of 238 patients having peripheral joint synovitis of
less than 12 months duration was evaluated clinically and followed prospectively for 1 year …
less than 12 months duration was evaluated clinically and followed prospectively for 1 year …
Expression and function of wingless and frizzled homologs in rheumatoid arthritis
M Sen, K Lauterbach, H El-Gabalawy… - Proceedings of the …, 2000 - National Acad Sciences
Rheumatoid arthritis (RA) is accompanied by synovial inflammation, proliferation, and
cartilage destruction. The reasons the activation of synovial fibroblasts often persists despite …
cartilage destruction. The reasons the activation of synovial fibroblasts often persists despite …
Hypoxia‐induced production of stromal cell–derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts
C Hitchon, K Wong, G Ma, J Reed, D Lyttle… - Arthritis & …, 2002 - Wiley Online Library
Objective Stromal cell–derived factor 1 (SDF‐1; or, CXCL12) is a potent chemotactic and
angiogenic factor that has been proposed to play a role in the recruitment of lymphocytes …
angiogenic factor that has been proposed to play a role in the recruitment of lymphocytes …
[HTML][HTML] A comparative study of the gut microbiota in immune-mediated inflammatory diseases—does a common dysbiosis exist?
Background Immune-mediated inflammatory disease (IMID) represents a substantial health
concern. It is widely recognized that IMID patients are at a higher risk for developing …
concern. It is widely recognized that IMID patients are at a higher risk for developing …
Antibodies to Porphyromonas gingivalis are associated with anticitrullinated protein antibodies in patients with rheumatoid arthritis and their relatives
CA Hitchon, F Chandad, ED Ferucci… - The Journal of …, 2010 - jrheum.org
Objective. Anticitrullinated protein antibodies (ACPA) are relatively specific for rheumatoid
arthritis (RA), and predate disease. The oral pathogen Porphyromonas gingivalis may play a …
arthritis (RA), and predate disease. The oral pathogen Porphyromonas gingivalis may play a …