Preventing progression from arthralgia to arthritis: targeting the right patients

HW Van Steenbergen, JAP Da Silva… - Nature Reviews …, 2018 - nature.com
Early treatment is associated with improved outcomes in patients with rheumatoid arthritis
(RA), suggesting that a'window of opportunity', in which the disease is most susceptible to …

Rheumatoid arthritis prevention in arthralgia: fantasy or reality?

HW van Steenbergen, AP Cope… - Nature Reviews …, 2023 - nature.com
The concept of a 'window of opportunity'in treating a disease assumes the existence of a
time frame during which the trajectory of the disease can be effectively and permanently …

EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis

HW van Steenbergen, D Aletaha… - Annals of the …, 2017 - ard.bmj.com
Background During the transition to rheumatoid arthritis (RA) many patients pass through a
phase characterised by the presence of symptoms without clinically apparent synovitis …

Clinical factors, anticitrullinated peptide antibodies and MRI-detected subclinical inflammation in relation to progression from clinically suspect arthralgia to arthritis

HW van Steenbergen, L Mangnus… - Annals of the …, 2016 - ard.bmj.com
Introduction Patients with clinically suspect arthralgia (CSA) have, according to their
rheumatologists, an increased risk of rheumatoid arthritis (RA), but their actual outcome is …

Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI

HW van Steenbergen, JAB van Nies… - Annals of the …, 2015 - ard.bmj.com
Background The phase of arthralgia is the earliest moment to clinically recognize patients
who may develop Rheumatoid Arthritis (RA). Previous imaging studies in the arthralgia …

Magnetic resonance imaging–detected features of inflammation and erosions in symptom‐free persons from the general population

L Mangnus, HW Van Steenbergen… - Arthritis & …, 2016 - Wiley Online Library
Objective The use of magnetic resonance imaging (MRI)–detected inflammation and joint
damage in the diagnosis of rheumatoid arthritis is recommended by a European League …

The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis: a study exploring replication and …

S Ajeganova, HW Van Steenbergen… - Annals of the …, 2017 - ard.bmj.com
Objective Anti-carbamylated protein (anti-CarP) antibodies are reported to associate with
more radiographic progression within the total rheumatoid arthritis (RA) population and anti …

Disease-modifying antirheumatic drug-free sustained remission in rheumatoid arthritis: an increasingly achievable outcome with subsidence of disease symptoms

S Ajeganova, HW Van Steenbergen… - Annals of the …, 2016 - ard.bmj.com
Objective Disease-modifying antirheumatic drug (DMARD)-free sustained remission, the
sustained absence of synovitis after cessation of DMARD therapy, is a relevant long-term …

[HTML][HTML] The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis

J Shi, HW van Steenbergen, JAB van Nies… - Arthritis research & …, 2015 - Springer
Introduction Anti-carbamylated protein (anti-CarP) antibodies have been described in
rheumatoid arthritis (RA) and arthralgia patients at risk of developing RA. To what extent …

Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey

SCM Stoof, HW Van Steenbergen… - …, 2015 - Wiley Online Library
Pregnant women with bleeding disorders require specialised peripartum care to prevent
postpartum haemorrhage (PPH). If third trimester coagulation factor levels are< 0.50 IU mL …