In murine ontogeny, macrophage precursor cells develop in the yolk sac and fetal liver.
Primitive macrophages also appear in the yolk sac, migrate to various tissues, and …

Abstract Storz, Jay F., and Hideaki Moriyama. Mechanisms of hemoglobin adaptation. High
Alt. Med. Biol. 9: 148–157, 2008.—Evidence from a number of vertebrate taxa suggests that …

Doxorubicin (DOX) is the most widely used anthracycline anticancer agent; however, its
cardiotoxicity limits its clinical efficacy. Numerous studies have elucidated the mechanisms …

A fundamental question about the pathogenesis of spontaneous autoimmune diabetes is
whether there are primary autoantigens. For type 1 diabetes it is clear that multiple islet …

The [URE3] nonchromosomal genetic element is an infectious form (prion) of the Ure2
protein, apparently a self-propagating amyloidosis. We find that an insertion mutation or …

Publisher Summary The presence of the four distinct seasons with appropriate temperature
and humidity in Japan surrounded by sea fostered the Japanese food eating habit and …

Ternary Mg90. 5Ni3. 25Y6. 25 (at.%) cast alloy consisting of a long-period ordered (LPO)
phase and α-Mg was rolled to 70% thickness reduction at 623K. After annealing at 673K for …

The 2.8 Å crystal structure of hydroxylamine oxidoreductase of a nitrifying chemoautotrophic
bacterium, Nitrosomonas europaea, is described. Twenty-four haems lie in the centre bottom …

Background: Eosinophils and nasal polyps are believed to affect the surgical outcome of
chronic rhinosinusitis (CRS). CRS is classified based on the presence of nasal polyps in …

Recent studies have shown that Notch signaling plays an important role in epidermal
development, but the underlying molecular mechanisms remain unclear. Here, by …