Immunoglobulins in systemic sclerosis management. A large multicenter experience

…, JJ Alegre-Sancho, G Bonilla, C Moriano… - Autoimmunity …, 2023 - Elsevier
Objective To analyze the effectiveness and safety of intravenous immunoglobulin (IVIG)
given in routine care to patients with systemic sclerosis (SSc). Methods A retrospective …

Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice

…, S Castañeda, I Villa, A Humbría, C Moriano… - Seminars in arthritis and …, 2019 - Elsevier
Objective: Tocilizumab (TCZ) has shown efficacy in clinical trials on giant cell arteritis (GCA).
Real-world data are scarce. Our objective was to assess efficacy and safety of TCZ in …

Tocilizumab in refractory giant cell arteritis. Monotherapy versus combined therapy with conventional immunosuppressive drugs. Observational multicenter study of …

…, S Castañeda, V Aldasoro, I Villa, C Moriano… - Seminars in Arthritis and …, 2021 - Elsevier
Objective To compare the efficacy and safety of TCZ in monotherapy (TCZ MONO) vs.
combined with conventional immunosuppressive drugs (TCZ COMBO) in Giant Cell Arteritis …

Tocilizumab in visual involvement of giant cell arteritis: a multicenter study of 471 patients

J Loricera, S Castañeda, C Moriano… - Therapeutic …, 2022 - journals.sagepub.com
Background: Visual involvement is the most feared complication of giant cell arteritis (GCA).
Information on the efficacy of tocilizumab (TCZ) for this complication is scarce and …

[PDF][PDF] The presence of both HLA-DRB1* 04: 01 and HLA-B* 15: 01 increases the susceptibility to cranial and extracranial giant cell arteritis

…, S Romero-Yuste, C Moriano… - Clin Exp …, 2021 - clinexprheumatol.org
Objective. To determine if patients with the predominant extracranial largevessel vasculitis
(LVV) pattern of giant cell arteritis (GCA) have a distinctive HLA-B association, different from …

[PDF][PDF] Optimisation of tocilizumab therapy in giant cell arteritis. A multicentre real-life study of 471 patients

M Calderón-Goercke, J Loricera, C Moriano… - Clin Exp …, 2022 - clinexprheumatol.org
Objective Tocilizumab (TCZ) is the only biologic therapy approved for giant cell arteritis
(GCA). There is general agreement on the initial/maintenance dose, duration of TCZ therapy …

[HTML][HTML] HLA association with the susceptibility to anti-synthetase syndrome

…, FJ López-Longo, L Lera-Gómez, C Moriano… - Joint Bone Spine, 2021 - Elsevier
Objective To investigate the human leukocyte antigen (HLA) association with anti-
synthetase syndrome (ASSD). Methods We conducted the largest immunogenetic HLA …

Cranial and extracranial giant cell arteritis share similar HLA-DRB1 association

…, F Ortiz-Sanjuán, S Romero-Yuste, C Moriano… - Seminars in arthritis and …, 2020 - Elsevier
Objective To determine whether giant cell arteritis (GCA) patients with the typical pattern of
cranial ischemic manifestations and those with the extracranial large-vessel-vasculitis (LVV) …

Apremilast in refractory orogenital ulcers and other manifestations of Behçet's disease. National multicenter study of 51 cases in clinical practice.

…, JL Martín-Varillas, J Graña, G Espinosa, C Moriano… - 2020 - researchsquare.com
Background Oral and/or genital aphthous ulcers are the most common symptoms of Behçets
disease (BD), and are often refractory to conventional treatment. The inhibitor of …

Vascular endothelial growth factor haplotypes are associated with severe ischaemic complications in giant cell arteritis regardless of the disease phenotype.

…, S Romero-Yuste, C Moriano… - Clinical and …, 2022 - europepmc.org
Objectives To determine whether functional vascular endothelial growth factor (VEGF)
polymorphisms influence the expression of the clinical phenotype of giant cell arteritis …