Genetics of rheumatoid arthritis contributes to biology and drug discovery

…, A Zhernakova, REM Toes, PP Tak, C Miceli-Richard… - Nature, 2014 - nature.com
A major challenge in human genetics is to devise a systematic strategy to integrate disease-
associated variants with diverse genomic and biological data sets to provide insight into …

2018 update of French Society for Rheumatology (SFR) recommendations about the everyday management of patients with spondyloarthritis

…, L Gossec, P Goupille, C Hudry, C Miceli-Richard… - Joint Bone Spine, 2018 - Elsevier
Abstract Objective To update French Society for Rheumatology recommendations about the
management in clinical practice of patients with spondyloarthritis (SpA). SpA is considered …

CARD15 mutations in Blau syndrome

C Miceli-Richard, S Lesage, M Rybojad, AM Prieur… - Nature …, 2001 - nature.com
We have identified three missense mutations in the nucleotide-binding domain (NBD) of
CARD15/NOD2 in four French and German families with Blau syndrome. Our findings …

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

…, JA Kelly, MG Dozmorov, C Miceli-Richard… - Nature …, 2013 - nature.com
Sjögren's syndrome is a common autoimmune disease (affecting∼ 0.7% of European
Americans) that typically presents as keratoconjunctivitis sicca and xerostomia. Here we …

Tumour necrosis factor α− 308G→ A polymorphism is not associated with response to TNFα blockers in Caucasian patients with rheumatoid arthritis: systematic …

S Pavy, EJM Toonen, C Miceli-Richard… - Annals of the …, 2010 - ard.bmj.com
Background There is a need for biomarkers that can predict anti-tumour necrosis factor (anti-
TNF) treatment outcome in patients with rheumatoid arthritis (RA). Several studies have …

[PDF][PDF] Qualifying unmet needs and improving standards of care in psoriatic arthritis

…, H Schulze‐Koops, C MiceliRichard… - Arthritis care & …, 2014 - Wiley Online Library
PHILIP HELLIWELL, 1 LAURA COATES, 2 VINOD CHANDRAN, 3 DAFNA GLADMAN, 3
MAARTEN DE WIT, 4 OLIVER FITZGERALD, 5 ARTHUR KAVANAUGH, 6 VIBEKE …

[HTML][HTML] B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary …

M Ittah, C Miceli-Richard, J Eric Gottenberg… - Arthritis research & …, 2006 - Springer
B cell-activating factor (BAFF) has a key role in promoting B-lymphocyte activation and
survival in primary Sjögren's syndrome (pSS). The cellular origin of BAFF overexpression in …

[HTML][HTML] Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease …

…, V Proulle, A Jüngel, M Ittah, C Miceli Richard… - Arthritis research & …, 2009 - Springer
Introduction Cell stimulation leads to the shedding of phosphatidylserine (PS)-rich
microparticles (MPs). Because autoimmune diseases (AIDs) are characterized by cell …

[PDF][PDF] Symptomatic efficacy of etanercept and its effects on objective signs of inflammation in early nonradiographic axial spondyloarthritis: a multicenter, randomized …

…, G Citera, C MiceliRichard… - Arthritis & …, 2014 - Wiley Online Library
Objective To assess the efficacy of etanercept in the treatment of early active nonsteroidal
antiinflammatory drug (NSAID)–refractory nonradiographic axial spondyloarthritis (SpA) …

[HTML][HTML] Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome …

JE Gottenberg, R Seror, C Miceli-Richard… - PloS one, 2013 - journals.plos.org
Objectives To analyze the clinical and immunological characteristics at enrollment in a large
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …