Mucosal FOXP3-Expressing CD4+ CD25high Regulatory T Cells in Helicobacter pylori-Infected Patients

A Lundgren, E Strömberg, A Sjöling… - Infection and …, 2005 - Am Soc Microbiol
Helicobacter pylori chronically colonizes the stomach and duodenum and causes peptic
ulcers or gastric adenocarcinoma in 10 to 20% of infected individuals. We hypothesize that …

Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina

C Bergquist, EL Johansson, T Lagergård… - Infection and …, 1997 - Am Soc Microbiol
Forty-five volunteers were vaccinated twice intranasally with 10, 100, or 1,000 microg of
cholera toxin B subunit (CTB). Blood and nasal and vaginal secretions were collected before …

Characterization of human CD25+ CD4+ T cells in thymus,
cord and adult blood

K Wing, A Ekmark, H Karlsson, A Rudin… - …, 2002 - Wiley Online Library
Summary CD4+ CD25+ regulatory T cells prevent organ‐specific autoimmune diseases in
various animal models. We analysed human lymphoid tissues to identify similar CD25+ …

Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity

N Holmén, A Lundgren, S Lundin… - Inflammatory bowel …, 2006 - academic.oup.com
Background Factors determining the extension and degree of inflammation in the colonic
mucosa of patients with ulcerative colitis (UC) are largely unknown, but CD4+ CD25high …

Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora

H Karlsson, C Hessle, A Rudin - Infection and Immunity, 2002 - Am Soc Microbiol
The hygiene hypothesis postulates that the prevalence of allergy has increased due to
decreased microbial stimulation early in life, leading to delayed maturation of the immune …

Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans

EL Johansson, L Wassén, J Holmgren… - Infection and …, 2001 - Am Soc Microbiol
Sexually transmitted diseases are a major health problem worldwide, but there is still a lack
of knowledge about how to induce an optimal immune response in the genital tract of …

Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS)

AL Herrick, X Pan, S Peytrignet, M Lunt… - Annals of the …, 2017 - ard.bmj.com
Objectives The rarity of early diffuse cutaneous systemic sclerosis (dcSSc) makes
randomised controlled trials very difficult. We aimed to use an observational approach to …

Infant B cell memory differentiation and early gut bacterial colonization

AC Lundell, V Björnsson, A Ljung, M Ceder… - The Journal of …, 2012 - journals.aai.org
Germ-free animal models have demonstrated that commensal bacterial colonization of the
intestine induces B cell differentiation and activation. Whether colonization with particular …

[HTML][HTML] Pet-keeping in early life reduces the risk of allergy in a dose-dependent fashion

B Hesselmar, A Hicke-Roberts, AC Lundell… - PloS one, 2018 - journals.plos.org
Objectives Several studies have indicated that early pet keeping could protect the infant from
later allergy development. Here, we investigate if there is a dose-dependent association …

Pattern of cytokine responses to gram‐positive and gram‐negative commensal bacteria is profoundly changed when monocytes differentiate into dendritic cells

H Karlsson, P Larsson, AE Wold… - Scandinavian Journal of …, 2004 - Wiley Online Library
The normal gastrointestinal flora is crucial for the maturation of the acquired immunity via
effects on antigen‐presenting cells (APCs). Here, we have investigated how two types of …