COVID-19 and autoimmune diseases
Y Liu, AH Sawalha, Q Lu - Current opinion in rheumatology, 2021 - journals.lww.com
We present a review of the association between COVID-19 and autoimmune diseases,
focusing on similarities in immune responses, cross-reactivity of SARS-CoV-2, the …
focusing on similarities in immune responses, cross-reactivity of SARS-CoV-2, the …
COVID-19: A review of therapeutic strategies and vaccine candidates
The world is engulfed by one of the most widespread and significant public health crises in
decades as COVID-19 has become among the leading causes of death internationally. The …
decades as COVID-19 has become among the leading causes of death internationally. The …
Impaired DNA methylation and its mechanisms in CD4+ T cells of systemic lupus erythematosus
Y Zhang, M Zhao, AH Sawalha, B Richardson… - Journal of autoimmunity, 2013 - Elsevier
Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by
production of autoantibodies against a series of nuclear antigens. Although the exact cause …
production of autoantibodies against a series of nuclear antigens. Although the exact cause …
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Monozygotic (MZ) twins are partially concordant for most complex diseases, including
autoimmune disorders. Whereas phenotypic concordance can be used to study heritability …
autoimmune disorders. Whereas phenotypic concordance can be used to study heritability …
Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients
AH Sawalha, M Zhao, P Coit, Q Lu - Clinical Immunology, 2020 - Elsevier
Infection caused by SARS-CoV-2 can result in severe respiratory complications and death.
Patients with a compromised immune system are expected to be more susceptible to a …
Patients with a compromised immune system are expected to be more susceptible to a …
Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus …
Systemic lupus erythematosus is an autoimmune disease characterized by multi-system
involvement and autoantibody production. Abnormal T cell DNA methylation and type-I …
involvement and autoantibody production. Abnormal T cell DNA methylation and type-I …
Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
Systemic lupus erythematosus is a chronic-relapsing autoimmune disease of incompletely
understood etiology. Recent evidence strongly supports an epigenetic contribution to the …
understood etiology. Recent evidence strongly supports an epigenetic contribution to the …
[PDF][PDF] Identification of multiple genetic susceptibility loci in Takayasu arteritis
Takayasu arteritis is a rare inflammatory disease of large arteries. The etiology of Takayasu
arteritis remains poorly understood, but genetic contribution to the disease pathogenesis is …
arteritis remains poorly understood, but genetic contribution to the disease pathogenesis is …
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus
AH Sawalha, KM Kaufman, JA Kelly, AJ Adler… - Annals of the …, 2008 - ard.bmj.com
Objective: The aetiology of systemic lupus erythematosus (SLE) is incompletely understood.
Both genetic and environmental factors are implicated in the pathogenesis of the disease …
Both genetic and environmental factors are implicated in the pathogenesis of the disease …
IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus
M Zhao, Y Zhou, B Zhu, M Wan, T Jiang… - Annals of the …, 2016 - ard.bmj.com
Objective Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease with
limited reliable diagnostic biomarkers. We investigated whether gene methylation could …
limited reliable diagnostic biomarkers. We investigated whether gene methylation could …