Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis

Hum Gene Ther. 1996 Jun 20;7(10):1261-80. doi: 10.1089/hum.1996.7.10-1261.

Authors

C H Evans¹, P D Robbins, S C Ghivizzani, J H Herndon, R Kang, A B Bahnson, J A Barranger, E M Elders, S Gay, M M Tomaino, M C Wasko, S C Watkins, T L Whiteside, J C Glorioso, M T Lotze, T M Wright

Affiliation

¹ Department of Molecular Genetics & Biochemistry, University of Pittsburgh School of Medicine, USA.

PMID: 8793551
DOI: 10.1089/hum.1996.7.10-1261

No abstract available

Publication types

Clinical Trial

MeSH terms

Arthritis, Rheumatoid / therapy*
Cell Transplantation
Clinical Protocols
Feasibility Studies
Gene Transfer Techniques*
Genetic Therapy* / methods
Humans
Interleukin 1 Receptor Antagonist Protein
Interleukin-1 / antagonists & inhibitors*
Metacarpophalangeal Joint
Sialoglycoproteins / genetics*
Sialoglycoproteins / therapeutic use
Synovial Fluid / cytology

Substances

IL1RN protein, human
Interleukin 1 Receptor Antagonist Protein
Interleukin-1
Sialoglycoproteins